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Akt Signaling Pathway
The phosphatidylinositol 3' -kinase(PI3K)-Akt signaling pathway is activated by many types of stimuli and controls fundamental cellular processes such as apoptosis, metabolism, proliferation, protein synthesis, growth, and survival. Dysregulation of this pathway is implicated in a number of disease states including cardiovascular and neurological disease, diabetes, and particularly cancer. This has led to the development of a number of small molecule inhibitors of both PI3K and Akt for use in therapeutic treatment of some of these diseases.
Featured Akt Pathway Products
- AKT Pathway Phosphorylation Array C1 - Detects 18 different phosphorylated human and mouse proteins crucial to the AKT Pathway.
- Human/Mouse/Rat Phospho-AKT (S473) ELISA - Semi-quantitatively measures phophorylated Akt (Ser473) in lysate samples.
- Akt Activity Assay Kit, KinaseSTAR - Detection of Akt1, Akt2, and Akt3 activities
Click on the targets in the map below to find RayBiotech products related to the Akt Signaling Pathway