Mouse anti-Human ALDH1 Antibody [Sodium Azide Free]

Mouse anti-Human ALDH1 Antibody [Sodium Azide Free]

188-11449-SAF
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Antigen Information

Accession Number:
  • P00352
Gene ID:
  • 216
Gene Symbols:
  • ALDC
  • ALDH1
  • ALDH1A1
  • PUMB1
Protein Name & Synonyms:
Retinal dehydrogenase 1 (RALDH 1) (RalDH1) (EC 1.2.1.-) (EC 1.2.1.36) (ALDH-E1) (ALHDII) (Aldehyde dehydrogenase family 1 member A1) (Aldehyde dehydrogenase, cytosolic)
Target Species:
  • Human

Antibody Specifications

Applications:
FACS: 0.5-1ug/10^6 cells
Western blot: 1-2ug/ml
IF: 1-2ug/ml
IHC (FFPE): 0.5-1ug/ml
Concentration:
1 mg/ml in 1X PBS (pH 7.4), BSA free, sodium azide free
Domain/Region/Terminus:
Cytoplasmic
Host Species:
Mouse
Preparation:
A human partial recombinant ALDH1A1 protein (AA 315-434) was used as the immunogen for this ALDH1 antibody.
Purity:
Protein G affinity chromatography
Species Reactivity:
Human. Others not tested.

Description

ALDH1A1 belongs to the ALDH enzymes, a family of evolutionarily conserved enzymes comprised of 19 isoforms that are localized in the cytoplasm, mitochondria or nucleus. ALDH1 is predominantly expressed in the epithelium of testis, brain, eye, liver, kidney, as well as neural and hematopoietic stem cells. Reportedly, high ALDH1 expression is found in solitary fibrous tumor (SFT) and hemangiopericytoma (HPC), compared to meningiomas and synovial sarcomas. In combination with CD34, ALDH1 may be useful for the differentiation among SFT, HPC, meningioma, and synovial sarcoma.

Storage

The antibody is stable for at least 1 year from the date of receipt when stored at -20°C to -70°C. Reconstituted antibody can also be aliquotted and stored at 4°C for 1 month or at -20°C to -70°C in a manual defrost freezer for many months without detectable loss activity. Please avoid freeze-thaw cycles.

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.