IHC testing of FFPE ovarian carcinoma with TFF1 antibody (clone BCEIP1).

Mouse anti-Human TFF1 Antibody

Mouse anti-Human TFF1 Antibody


Antigen Information

Accession Number:
  • P04155
Gene ID:
  • 7031
Gene Symbols:
  • BCEI
  • PS2
  • TFF1
Protein Name & Synonyms:
Trefoil factor 1 (Breast cancer estrogen-inducible protein) (PNR-2) (Polypeptide P1.A) (hP1.A) (Protein pS2)
Target Species:
  • Human

Antibody Specifications

Immunofluorescence: 0.5-1ug/ml
Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT (1)
Prediluted format: incubate for 30 min at RT (2)
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Host Species:
A C-terminus peptide was used as the immunogen for the TFF1 antibody.
Protein G affinity chromatography
Species Reactivity:
Human. Other species not tested.
Mouse IgG1, kappa


TFF1/Breast cancer estrogen inducible protein pS2 is a trefoil peptide. Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intra-chain disulfide bonds, forming the trefoil motif, or P-domain. TFF1/pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. About 60% of breast carcinomas are positive for pS2. Staining is cytoplasmic, often with localization to the Golgi apparatus. TFF1 is shown to be localized in normal stomach mucosa, gastric fluid, goblet cells in the colon and small intestine, and in ulcerations of the gastrointestinal tract.


The antibody is stable for at least 1 year from the date of receipt when stored at -20°C to -70°C. Reconstituted antibody can also be aliquotted and stored at 4°C for 1 month or at -20°C to -70°C in a manual defrost freezer for many months without detectable loss activity. Please avoid freeze-thaw cycles.

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This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.