Sterile filtered solution (1 mg/ml) in 10 mM Tris, pH 8.0, 0.1% Triton X-100 and 0.002% NaN3.
&ge,95% determined by SDS-PAGE, &ge,95% determined by HPLC
Protein Name & Synonyms:
Acetyl-CoA acetyltransferase cytosolic, Cytosolic acetoacetyl-CoA thiolase, ACAT2, Acetyl CoA transferase-like protein, ACAT-2, Sterol O-acyltransferase 2, Acyl-coenzyme A:cholesterol acyltransferase 2, Cholesterol acyltransferase 2
Molecular Weight (kDa):
Acetyl-Coenzyme A acetyltransferase 2 (ACAT2) is an enzyme involved in lipid metabolism. Patients with ACAT2 deficiency have shown severe mental retardation and hypotonus. The ACAT2 gene shows complementary overlapping with the 3 prime region of the TCP1 gene in both mouse and human. These genes are encoded on opposite strands of DNA, as well as in opposite transcriptional orientation.
The protein may be stored for 12 months at -20°C