Active AHCY, Human recombinant

$301.00
268-11117-1
+

Source

Gene Symbols:
  • AHCY
Species:
Human
Accession Number:
  • P23526
Gene ID:
  • 191
Protein Name & Synonyms:
AHCY/SAHH, SAHH, AdoHcyase, S-adenosyl-L-homocysteine hydrolase, Adenosyl Homocysteinase

Preparation

Expression System:
E.Coli
Purity:
&ge,90% determined by SDS-PAGE
Molecular Weight (kDa):
52.1 kDa (1-432 aa + N-terminal polyhistidine tag). In the native form the protein exists in the tetrameric form and this form is required for activity.

Protein Specifications

Format:
5 mg/ml in 50 mM potassium phosphate, 1 mM EDTA, pH 7.2 containing 20% glycerol.
Concentration:
5 mg/ml

Introduction

AHCY (EC 3.3.1.1) is an enzyme that catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). AHCY controls the intracellular S-adenosylhomocysteine (SAH) concentration that is crucial for transmethylation reactions. AHCY deficiency causes hypermethioninemia. The recombinant human AHCY produced in E.Coli is a single, non-glycosylated polypeptide chain and is purified by proprietary chromatographic techniques.

Stability & Storage

Shipping
Gel Pack
Storage/Stability
The protein may be stored for 6 months at -80°C

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.