Adiponectin, Mouse Recombinant, Trimeric form

$198.00  
228-20155-2
+

Product Specifications

Size:
10 ug or 1 mg
Format:
Filtered white lyophilized (freeze-dried) powder.
Formulation:
Mouse Acrp30 filtered (0.4 um) and lyophilized from 0.5 mg/ml in 0.05M phosphate buffer, 0.05M NaCl, pH 7.2.
Purity:
Acrp30 Mouse purity is greater than 95% as determined by SDS-PAGE.

Source

Accession Number:
  • Q60994
Gene ID:
  • 11450
Protein Name & Synonyms:
Acrp30, AdipoQ, GBP-28, APM-1, ACDC.

Preparation

Expression System:
HEK 293 cells

Introduction

Adiponectin is a hormone exclusively expressed from adipose tissue. Many studies demonstrate that adiponectin has direct anti-diabetic, anti-atherogenic and anti-inflammatory functions. APM-1 can increase insulin sensitivity of skeletal muscle, attenuate hepatic lipogenesis and luconeogenesis, regulate NO production in endothelial cells, inhibit proliferation of smooth muscle cells and prevent lipid accumulation of macrophage cells.In the circulation, adiponectin is present as three different oligomeric complexes, including the high molecular weight (HMW), the middle molecular weight (MMW, also called hexamer) and low molecular weigh (MMW, also called trimer) forms 8. Different oligomeric complex of adiponectin activates different signaling pathways and exerts distinct functions.

Description

Trimeric form of Acrp30 Mouse was expressed in HEK293 cells.The cysteine 39 was replaced with alanine (C39A) 9. mAd-C39A can only form trimer, but not hexamer or HMW form.

Stability & Storage

Storage/Stability
Store lyophilized Acrp30 Mouse at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted Acrp30 Mouse can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C.

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.