Angiotensin I Converting Enzyme 2 (ACE2)

Angiotensin I Converting Enzyme 2 (ACE2) is an endogenous receptor that is required for SARS-CoV-2 entry. Neuropilin-1 (NRP1) also facilitates in viral entry.

ACE2 Protein
Figure 1. Human ACE2 domains
SP = Signal peptide; TM = transmembrane domain; ID = Intracellular domain

Recombinant ACE2 Protein

Catalog # Species Protein Domain Purification Expression Host Expression Region Tag MW (kDa)
230-30165 Human Extracellular domain Purified HEK293 Cell Gln18-Ser740 C-terminal His-tag ∼90 kDa
230-20410 Human Extracellular domain Unpurified HEK293 Cell Gln18-Ser740 C-terminal His-tag ∼90 kDa
230-30177 Mouse Extracellular domain Purified HEK293 Cell Gln18-Thr740 C-terminal His-tag ∼90 kDa