Autoimmunity & Inflammation

Understanding the Role of Inflammatory Proteins in Disease

Inflammation plays a crucial role in the pathogenesis of many diseases, including cancer, cardiovascular disease, and autoimmune disorders. Inflammatory proteins/cytokines regulate immune and inflammatory responses and are key players in the development and progression of these diseases.

RayBiotech has a large catalog of inflammation research products, including ELISA kits, antibody arrays, and flow cytometry reagents for immune response research. Full testing services are available for all RayBiotech products, including flow cytometry.

Flow cytometry analysis of specific T helper cell populations, including Th1, Th2, Th17 and Tregs.

Inflammation Antibody Arrays

As a leading provider of high-quality research tools and technologies, we understand the importance of multiplex inflammation arrays in the study of inflammatory processes and the identification of potential biomarkers for various diseases.

We offer inflammation / autoimmune antibody arrays for multiple species that enable researchers to simultaneously measure the expression of up to 40 cytokines in a single sample. Our arrays are highly sensitive and specific, and they allow for the identification of novel biomarkers and the characterization of complex signaling networks.

Featured Publications

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    Staedtke V., Bai R., Kim K., et al. Disruption of a self-amplifying catecholamine loop reduces cytokine release syndrome. Nature. 2018 Dec;564(7735):273-277. doi: 10.1038/s41586-018-0774-y
    Species: Mouse
    Sample type: Conditioned Media (C nogyi NT treated cells)

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    Grubiši? V, McClain JL, Fried DE, Grants I, Rajasekhar P, Csizmadia E, Ajijola OA, Watson RE, Poole DP, Robson SC, Christofi FL, Gulbransen BD. Enteric Glia Modulate Macrophage Phenotype and Visceral Sensitivity following Inflammation. Cell Rep. 2020 Sep 8;32(10):108100. doi: 10.1016/j.celrep.2020.108100. PMID: 32905782; PMCID: PMC7518300.
    Species: Human
    Sample type: Conditioned Media (Primary Fibroblasts in cancer model)

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    Han Lu , Hui-Li Yang , Wen-Jie Zhou , Zhen-Zhen Lai , Xue-Min Qiu , Qiang Fu , Jian-Yuan Zhao , Jian Wang , Da-Jin Li & Ming-Qing Li (2020): Rapamycin prevents spontaneous abortion by triggering decidual stromal cell autophagy-mediated NK cell residence, Autophagy, DOI: 10.1080/15548627.2020.1833515
    Species: Human
    Sample type: Conditioned media (Cell culture supernatants)

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    Biemmi V, Milano G, Ciullo A, Cervio E, Burrello J, Dei Cas M, Paroni R, Tallone T, Moccetti T, Pedrazzini G, Longnus S, Vassalli G, Barile L. Inflammatory extracellular vesicles prompt heart dysfunction via TRL4-dependent NF-?B activation. Theranostics. 2020 Feb 3;10(6):2773-2790. doi: 10.7150/thno.39072. PMID: 32194834; PMCID: PMC7052909.
    Species: Rat
    Sample type: Tissue Lysate

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    Yang, Y., Guo, X., Hu, B., He, P., Jiang, X., Wang, Z., Feng, M. (2020). Generated SecPen_NY-ESO-1_ubiquitin-pulsed dendritic cell cancer vaccine elicits stronger and specific T cell immune responses. Acta Pharmaceutica Sinica B. doi:10.1016/j.apsb.2020.08.004 
    Species: mouse
    Sample type: Cell Lysate (Cultivated PBMC cells with NY-ESO protein)

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    Ogita, T., Yamamoto, Y., Mikami, A., et al. Oral Administration of Flavonifractor plautii Strongly Suppresses Th2 Immune Responses in Mice. Front Immunol. 2020; 11: 379. doi: 10.3389/fimmu.2020.00379
    Species: Mouse
    Sample type: Conditioned Media (Splenocytes T cells incubated with DCs)

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