Infectious Disease & Vaccines
Proteomic Tools to Advance Your Infectious Disease Research
Infectious diseases are transmitted from person-to-person or from animals to humans. The diseases are caused by bacteria and viruses, and cause an immune response that is often characterized by inflammation. These pathogens can be transmitted by air, physical contact, or touching an item that an infected person has touched. Infectious diseases can become an epidemic if there is a sudden increase in cases, or a pandemic if the disease infects many people across several continents. Also known as communicable diseases, infectious diseases are defined by a value called R-naught (R0) to gauge how severe an outbreak may be. The R0 reflects how many people a single infected person is likely to infect.
RayBiotech provides a wide range of advanced tools that allow researchers to gain a deeper understanding of diseases, from their causes to their potential cures / vaccine development. Disease proteomic research tools are specifically designed to help researchers better understand the proteins involved in diseases. From long-standing diseases, such as cancer and Alzheimer's, to recent pandemics, such as COVID-19 and Monkeypox, we pride ourselves on developing innovative research tools and services as soon as (or even before) researchers realize they need them.
Identify disease protein biomarkers and gain insights into mechanisms and pathways.
See the citations below that used our ELISAs, arrays, and recombinant proteins to publish their findings related to infectious disease research.
Park, H. T., Park, H. E., Shim, S., Kim, S., Shin, M. K., & Yoo, H. S. (2020). Epithelial processed Mycobacterium avium subsp. paratuberculosis induced prolonged Th17 response and suppression of phagocytic maturation in bovine peripheral blood mononuclear cells. Scientific reports, 10(1), 21048.
Wozniak JM, Mills RH, Olson J, Caldera JR, Sepich-Poore GD, Carrillo-Terrazas M, Tsai CM, Vargas F, Knight R, Dorrestein PC, Liu GY, Nizet V, Sakoulas G, Rose W, Gonzalez DJ. Mortality Risk Profiling of Staphylococcus aureus Bacteremia by Multi-omic Serum Analysis Reveals Early Predictive and Pathogenic Signatures. Cell. 2020 Sep 3;182(5):1311-1327.e14. doi: 10.1016/j.cell.2020.07.040. PMID: 32888495; PMCID: PMC7494005.
Drolia R., Tenguria S., Durkes A., et al. Listeria Adhesion Protein Induces Intestinal Epithelial Barrier Dysfunction for Bacterial Translocation. Cell Host Microbe. 2018 Apr 11;23(4):470-484.e7. doi: 10.1016/j.chom.2018.03.004.
Drolia R, Amalaradjou MAR, Ryan V, Tenguria S, Liu D, Bai X, Xu L, Singh AK, Cox AD, Bernal-Crespo V, Schaber JA, Applegate BM, Vemulapalli R, Bhunia AK. Receptor-targeted engineered probiotics mitigate lethal Listeria infection. Nat Commun. 2020 Dec 11;11(1):6344. doi: 10.1038/s41467-020-20200-5. PMID: 33311493; PMCID: PMC7732855.
Richard-Greenblatt M, Boillat-Blanco N, Zhong K, Mbarack Z, Samaka J, Mlaganile T, Kazimoto T, D’acremont V, Kain KC. Prognostic Accuracy of Soluble Triggering Receptor Expressed on Myeloid Cells (sTREM-1)-based Algorithms in Febrile Adults Presenting to Tanzanian Outpatient Clinics. Clin Infect Dis. 2020 Mar 17;70(7):1304-1312. doi: 10.1093/cid/ciz419. PMID: 31102510.