CCL14/HCC-1/HCC-3, Human recombinant

$255.00
268-10195-1
+

Source

Gene Symbols:
  • CCL14
Species:
Human
Accession Number:
  • Q16627
Gene ID:
  • 6358
Expressed Region:
Target protein is expressed with sequence (Thr20-Asn93) of Human hcc-1 (Uniprot #Q16627) fused with a polyhistidine tag at the C-terminus.
Protein Name & Synonyms:
CCL-14, C-C motif chemokine 14, Chemokine CC-1/CC-3, HCC-1/HCC-3, HCC-1(1-74), NCC-2, Small-inducible cytokine A14, Cleaved into: HCC-1(3-74), HCC-1(4-74), HCC-1(9-74)

Preparation

Expression System:
Mammalian cell expression system
Purity:
&ge,95% determined by SDS-PAGE, &ge,95% determined by HPLC
Molecular Weight (kDa):
~9.5 kDa

Protein Specifications

Format:
Lyophilized from a 0.2 um filtered solution of 20 mM PB and 150 mM NaCl, pH 7.2.
Endotoxin Level:
<0.1 ng/ug (1 IEU/ug)

Introduction

Chemokine (C-C motif) ligand 14 (CCL14) is a small cytokine belonging to the CC chemokine family. It is also commonly known as HCC-1. It is produced as a protein precursor that is processed to generate a mature active protein containing 74 amino acids that and is 46% identical in amino acid composition to CCL3 and CCL4. This chemokine is expressed in various tissues including spleen, bone marrow, liver, muscle, and gut. CCL14 activates monocytes, but does not induce their chemotaxis. Human CCL14 is located on chromosome 17 within a cluster of other chemokines belonging to the CC family.

Stability & Storage

Shipping
Gel pack
Storage/Stability
The protein may be stored for 12 months at -20°C

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.