Mouse Anti-Human Cortactin(Ascites)

Mouse Anti-Human Cortactin(Ascites) Antibody, 0.1 ml

$420.00  
102-10231
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Antigen Information

Accession Number:
  • Q14247
Gene ID:
  • 2017
Gene Symbols:
  • CTTN
Protein Name & Synonyms:
Cortactin(Ascites)
Target Species:
  • Human

Antibody Specifications

Preparation:
Purified His-tagged Cortactin protein(Fragment) was used to produced this monoclonal antibody.
Species Reactivity:
Human
Clonality:
Monoclonal

Introduction

This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene.

Specificity

Other Names
CTTN; EMS1; Src substrate cortactin; Amplaxin; Oncogene EMS1
NCBI Accession #
NP_001171669.1;NP_005222.2;NP_612632.1
Other Accession #
NP_005222.2

Format

Type
Mouse Monoclonal Antibody (Mab)
Calculated Molecular Weight (Da)
61586
Recommended Dilutions
WB: 1:1000-8000
Cortactin Antibody (Cat# 102-10231) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the Cortactin antibody detected the Cortactin protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.