Covid-19 Products

Accelerate your SARS-CoV-2 research and development with Covid-19 products and services that enable multiplexed, high-throughput, and quantitative studies.

Browse All COVID-19 Products

Research Tools You Can Rely On

Since becoming the first company to commercialize the planar protein array, we have been committed to helping our customers conduct their research more quickly, deeply, and with heightened confidence. The unprecedented challenge presented by the sudden and dramatic spread of SARS-CoV-2 led us to strengthen our commitment and expand our support for scientists like you.

Take advantage of our wide range of high-quality Covid-19 products which are manufactured and shipped from our facilities in the United states, for reliable quality and fast deliveries. From ELISA and PCR kits to patient samples and pseudovirus services, RayBiotech has everything you need to research SARS-CoV-2 from every vantage point.

Covid-19 Product Categories

Antibodies

Uncover the immune response to SARS-CoV-2 with monoclonal and polyclonal antibody detection and characterization.

ELISA Kits

Confidently detect SARS-CoV-2 IgG, IgM, and IgA antibodies with our indirect and sandwich ELISA kits.

PCR Kits

Skip RNA extraction or avoid PCR machines entirely with our innovative PCR kits.
OR
Verify the virus presence by visual color inspection with our rapid, convenient, and innovative PCR kits.

Binding Assays

Experience rapid, high throughput screening of Spike-receptor inhibitors that facilitate SARS-CoV-2 viral entry.

Proteins

Investigate structure and infection capacity with our comprehensive catalog of recombinant SARS-CoV-2 proteins.

Protein Arrays

Analyze antibody isotype binding to specific viral antigens in serum, plasma, and other liquid sample types.

Sample Collection

Easily collect samples for RNA, DNA, Antibody, and Protein analysis with our comprehensive collection kits.

Patient Samples

Safely accelerate your research with samples from acute & recovered COVID-19 patients.

Pseudovirus Service

Advance your discovery with cell culture research through our COVID-19 pseudovirus service.

Popular COVID-19

  1. Recombinant SARS-CoV-2 Omicron Variant BQ1.1 Spike S1 RBD Protein
    Recombinant SARS-CoV-2 Omicron Variant BQ1.1 Spike S1 RBD Protein Recombinant SARS-CoV-2 Omicron variant BQ1.1 spike S1 subunit receptor binding protein (RBD) with 20 mutant sites (G339H, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H) with C-terminal His-tag, derived from the transfected human HEK293 cells.
  2. Recombinant SARS-CoV-2 Omicron Variant BA.2.75.2 Spike S1 RBD Protein
    Recombinant SARS-CoV-2 Omicron Variant BA.2.75.2 Spike S1 RBD Protein Recombinant SARS-CoV-2 Omicron variant BA.2.75.2 spike S1 subunit receptor binding protein (RBD) with 19 mutant sites (G339H, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, G446S, N460K, S477N, T478K, E484A, F486S, Q498R, N501Y, Y505H) with C-terminal His-tag, derived from the transfected human HEK293 cells.
  3. Recombinant SARS-CoV-2 Omicron Variant BA.5 Spike S1 RBD Protein
    Recombinant SARS-CoV-2 Omicron Variant BA.5 Spike S1 RBD Protein Recombinant SARS-CoV-2 Omicron variant BA.5 spike S1 subunit receptor binding protein (RBD) with 16 mutant sites (G339D, S371F, S373P, S375F, T376A, D405N, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H) with C-terminal His-tag, derived from the transfected human HEK293 cells.
  4. Recombinant SARS-CoV-2 Omicron Variant BA.4 Spike S1 RBD Protein
    Recombinant SARS-CoV-2 Omicron Variant BA.4 Spike S1 RBD Protein Recombinant SARS-CoV-2 Omicron variant BA.4 spike S1 subunit receptor binding protein (RBD) with 17 mutant sites (G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H) with C-terminal His-tag, derived from the transfected human HEK293 cells.
  5. Recombinant SARS-CoV-2 S2 Subunit Protein (full length)
    Recombinant SARS-CoV-2 S2 Subunit Protein (full length) Recombinant SARS-CoV-2 S2 Subunit Protein with C-terminal tag, derived from the transfected human HEK293 cells.
    Datasheet
  6. Recombinant SARS Associated Coronavirus Envelope, His Tag
    Recombinant SARS Associated Coronavirus Envelope, His Tag SARS-Associated Coronavirus Envelope Recombinant, His Tag
  7. Mouse anti-SARS-COV-2-S1RBD (1H2-D8-A12)
    Mouse anti-SARS-COV-2-S1RBD (1H2-D8-A12)
  8. Mouse anti-SARS-COV-2-S1RBD (4E10-A11-A11)
    Mouse anti-SARS-COV-2-S1RBD (4E10-A11-A11)
  9. Mouse anti-SARS-COV-2-S1RBD (1H9-G1-A1)
    Mouse anti-SARS-COV-2-S1RBD (1H9-G1-A1)
  10. Rabbit anti-SARS-CoV-2 S2F antibody
    Rabbit anti-SARS-CoV-2 S2F antibody Polyclonal Rabbit antibody against SARS-CoV-2 (COVID-19) Spike Protein Subunit 2 (S2F) Protein
  11. Rabbit anti-SARS-CoV-2 N-Protein antibody
    Rabbit anti-SARS-CoV-2 N-Protein antibody Polyclonal Rabbit antibody against SARS-CoV-2 (COVID-19) Nucleocapsid Protein
  12. Rabbit anti-SARS-CoV-2 S1 RBD antibody
    Rabbit anti-SARS-CoV-2 S1 RBD antibody Polyclonal Rabbit antibody against SARS-CoV-2 (COVID-19) Spike Protein S1 Receptor Binding Domain

New Products

  1. Recombinant SARS-CoV-2 Omicron Variant BQ1.1 Spike S1 RBD Protein
    Recombinant SARS-CoV-2 Omicron Variant BQ1.1 Spike S1 RBD Protein Recombinant SARS-CoV-2 Omicron variant BQ1.1 spike S1 subunit receptor binding protein (RBD) with 20 mutant sites (G339H, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H) with C-terminal His-tag, derived from the transfected human HEK293 cells.
  2. Recombinant SARS-CoV-2 Omicron Variant BA.2.75.2 Spike S1 RBD Protein
    Recombinant SARS-CoV-2 Omicron Variant BA.2.75.2 Spike S1 RBD Protein Recombinant SARS-CoV-2 Omicron variant BA.2.75.2 spike S1 subunit receptor binding protein (RBD) with 19 mutant sites (G339H, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, G446S, N460K, S477N, T478K, E484A, F486S, Q498R, N501Y, Y505H) with C-terminal His-tag, derived from the transfected human HEK293 cells.
  3. Recombinant SARS-CoV-2 Omicron Variant BA.5 Spike S1 RBD Protein
    Recombinant SARS-CoV-2 Omicron Variant BA.5 Spike S1 RBD Protein Recombinant SARS-CoV-2 Omicron variant BA.5 spike S1 subunit receptor binding protein (RBD) with 16 mutant sites (G339D, S371F, S373P, S375F, T376A, D405N, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H) with C-terminal His-tag, derived from the transfected human HEK293 cells.
  4. Recombinant SARS-CoV-2 Omicron Variant BA.4 Spike S1 RBD Protein
    Recombinant SARS-CoV-2 Omicron Variant BA.4 Spike S1 RBD Protein Recombinant SARS-CoV-2 Omicron variant BA.4 spike S1 subunit receptor binding protein (RBD) with 17 mutant sites (G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H) with C-terminal His-tag, derived from the transfected human HEK293 cells.
  5. Recombinant SARS-CoV-2 S2 Subunit Protein (full length)
    Recombinant SARS-CoV-2 S2 Subunit Protein (full length) Recombinant SARS-CoV-2 S2 Subunit Protein with C-terminal tag, derived from the transfected human HEK293 cells.
    Datasheet
  6. Recombinant SARS-CoV-2 Omicron Variant B.1.1.529 Nucleocapsid (N) Protein
    Recombinant SARS-CoV-2 Omicron Variant B.1.1.529 Nucleocapsid (N) Protein Recombinant SARS-CoV-2 Omicron Variant B.1.1.529 Nucleocapsid (N), derived from the transfected human HEK293 cells.
  7. Recombinant SARS-CoV-2 Spike Protein Subunit 1, N-terminal with Fc tag
    Recombinant SARS-CoV-2 Spike Protein Subunit 1, N-terminal with Fc tag Recombinant SARS-CoV-2 Spike Protein Subunit 1, N-terminal domain, with a C-terminal mouse IgG Fc tag, derived from the transfected human HEK293 cells.
  8. Recombinant SARS-CoV-2 Replicase Polyprotein 1a (3C-like Proteinase Nsp5)
    Recombinant SARS-CoV-2 Replicase Polyprotein 1a (3C-like Proteinase Nsp5) Recombinant SARS-CoV-2 replicase polyprotein 1a (3C-like Proteinase Nsp5) derived from E.coli
  9. Recombinant SARS-CoV-2 S1 Subunit Protein RBD, R346K/E484K/N501Y mutant, Biotinylated
    Recombinant SARS-CoV-2 S1 Subunit Protein RBD, R346K/E484K/N501Y mutant, Biotinylated Biotin-conjugated recombinant SARS-CoV-2 S1 subunit protein RBD, mutant R346K/E484K/N501Y with C-terminal His-tag, derived from the transfected human HEK293 cells.
  10. Recombinant SARS-CoV-2 S1 Subunit Protein RBD, R346K mutant, Biotinylated
    Recombinant SARS-CoV-2 S1 Subunit Protein RBD, R346K mutant, Biotinylated Biotin-conjugated recombinant SARS-CoV-2 S1 subunit protein RBD, mutant R346K with C-terminal His-tag, derived from the transfected human HEK293 cells.
  11. Recombinant SARS-CoV-2 S1 Subunit Protein RBD, L452R/T478K mutant, Biotinylated
    Recombinant SARS-CoV-2 S1 Subunit Protein RBD, L452R/T478K mutant, Biotinylated Biotin-conjugated recombinant SARS-CoV-2 S1 subunit protein RBD, mutant L452R/T478K with C-terminal His-tag, derived from the transfected human HEK293 cells.
  12. Recombinant SARS-CoV-2 S1 Subunit Protein RBD, F490S mutant, Biotinylated
    Recombinant SARS-CoV-2 S1 Subunit Protein RBD, F490S mutant, Biotinylated Biotin-conjugated recombinant SARS-CoV-2 S1 subunit protein RBD, mutant F490S with C-terminal His-tag, derived from the transfected human HEK293 cells.

What customers are saying

“The kit [COVID-19 S-Protein (S1RBD) ELISA Kit Cat# ELV-COVID19S1] arrived very quickly and was very easy to use following the manual. I used plasma samples from various groups of patients and the results came out very nicely!”

Kailey

Boston Children’s Hospital

“​​I'm so glad I found these vaccinated samples on RayBiotech's website. I asked for specific details on these samples and got them within minutes! This is highly appreciated! Thank you!”

Netta

Almog Diagnostic

viral-particle

Featured Service

Covid-19 Pseudovirus Services

RayBiotech's COVID-19 pseudovirus service enables the study of the SARS-CoV-2 virus in cell culture. This service is ideal for screening patient serum for neutralizing antibodies and validating inhibitors of the Spike-ACE2 interaction.

View Pseudovirus Services

Covid-19 Biology 101

sars-cov-2-structure
Covid-19 Proteins

The outside of the SARS-CoV-2 viral particle is composed of 4 main proteins: spike (S), envelope (E), membrane (M), and nucleocapsid (N) protein.1 The S protein is required for the virus to enter human cells.

sars-cov-2-viral-entry
Viral Entry

The virus enters the cell through interactions with transmembrane proteins ACE2 and TMPRSS2.2

Besides being expressed on the surface of cells, ACE2 is also found in the lung, small intestine, and adipose tissue.3

general-antibody-profile
Immune Response

SARS-CoV-2 can trigger a "cytokine storm" in the lungs, characterized by a rapid, simultaneous release of several inflammatory proteins.4 This could explain tissue and organ damage that occurs during Covid-19.

throat-swab
Covid-19 Diagnosis

Antibodies, viral load, and clinical symptoms determine COVID-19 status. Physicians use two tests to achieve an accurate diagnosis: nucleic acid amplification tests (NAATs) that include qPCR tests and antigen tests.5

Achieve your objectives faster with custom testing services

Whether you’re short on time, short on resources, or just need a trusted expert to complete a stage in your research, we’ve got you covered. With our comprehensive suite of services, we’re excited to help you move your research and discovery studies forward.

Here are some of the top services that complement our Covid-19 products.

Quantitative Proteomics Services

Our experienced service department can quantitatively detect up to 1200 human, 640 mouse, 282 rat, 50 porcine, and 30 bovine proteins with our GLP-certified Quantibody® Multiplex ELISA platform.

Benefits:

  • Trust your findings with our automated slide processing system and careful, thorough data analysis that ensures efficient, high-quality, reproducible results.
  • Save money and run more tests with the Quantibody® Multiplex ELISA Array. More cost-effective than traditional ELISA!
  • Enjoy limitless customizations with assays suitable for diverse sample types.
  • Get more out of your samples with low sample volume requirements.
  • Confidently review your full report, complete with raw data and step-by-step calculations giving you insight into exactly what we did.

Curious how our quantitative proteomics services can help your labs?

Learn More
Discovery Proteomics Services

The discovery proteomics process allows for the identification of key proteins across multiple pathways and biological processes while minimizing time and effort. Once identified, these proteins can be verified and validated in a larger number of samples.

Design principles and service options:

  • Our assays can identify up to 6000 human, 1308 mouse, 1500 rat, 50 porcine, 30 bovine, or 500 rabbit proteins.
  • We offer two different types of array designs and can help you choose the best platform for your study needs:
    • Label-based platform for screening a large number of targets.

      We directly conjugate biotin to the proteins in your sample and detect proteins that bind to the array using a streptavidin-conjugated fluor. Because only a single antibody is used—the antibody immobilized to the slide—there is no need to optimize capture-detection antibody pairs, which removes a major constraint on array size.

    • Sandwich-based platform for sensitive detection.

      These arrays use a typical sandwich-ELISA design, where capture antibodies are printed on the slide and sample incubated with the array. Bound sample is detected by a cocktail of biotinylated detection antibodies and visualized by a streptavidin-conjugated fluor.

Want to see how our discovery proteomics services can advance your research?

Learn More

Small Molecules / Inhibitors

Name Catalog # CAS # Target Candidate
Arbidol HCl 331-11756 131707-23-8 Viral spike glycoprotein for binding to host cell receptor ACE2
Ritonavir 331-11642 155213-67-5 HIV Protease
Lopinavir 331-11643 192725-17-0 Coronavirus main protease 3CLpro
Darunavir 331-11645 206361-99-1 HIV Protease
Ribavirin 331-10301 36791-04-5 RNA-dependent RNA polymerase
Chloroquine diphosphate 331-11962 54-05-7 Malaria (endosome/ACE2)
Nitazoxanide 331-11871 55981-09-4 Viral protein expression
Camostat mesilate 332-10779 59721-29-8 Transmembrane protease, serine 2, primes S protein to facilitate its binding to ACE2
Hydroxychloroquine Sulfate 331-21357 747-36-4 Malaria (endosome/ACE2)
Baricitinib Phosphate 332-10769 1187595-84-1 JAK kinase that regulate the inflammatory processes

Publication Highlight: Researchers Trick Covid-19 with a Lung Spheroid Cell Decoy

Exploiting SARS-CoV-2’s use of the angiotensin-converting enzyme 2 (ACE2) for host cell entry, Zhenhua, et al., (Nat Nanotechnol. 2021 Aug;16(8):942-95) created lung spheroid cell (LSC) membrane nanovesicles coated with ACE2 to act as “nanodecoys” for virus binding. Since the LSC-nanodecoys bind to the SARS-CoV-2 spike (S) protein, they can compete with cell surface ACE2 for extracellular virus, generating LSC-nanodecoy-SARS-CoV-2 complexes that trigger a phagocytic response and viral elimination.

As a result, the LSC-nanodecoy may be able to prevent viral spread and mitigate damaging long-term effects of infection.

Furthermore, unlike SARS-CoV-2 variants that constantly mutate, ACE2 receptors on human host cells remain constant and unchanging, making this research particularly promising for treating Covid-19 throughout SARS-CoV-2 evolutions.

Zhenhua et al. used RayBiotech’s Mouse Cytokine Array C1000 to quickly and efficiently analyze their blood samples.

C-Series-Array-1000-Data

Cytokine array analysis of various inflammatory cytokines (j) in the serum 3 d after treatment: control (f), LSC-nanodecoy (g), SARS-CoV-2 mimic (h) and SARS-CoV-2 mimic plus LSC-decoy (i). IFN-γ, interferon γ; IL, interleukin; M-CSF, macrophage colony-stimulating factor; POS, positive control; TNF-α, tumor necrosis factor α.

Read the publication

Related Services

CRO Services

When you need a few extra hands to get an assay completed or support from experimental design to data analysis, our experienced team of scientists is ready to help.

Antibody Service

Leverage the same quality antibody production processes we put into our products for your custom research and bulk antibody production needs.

ELISA Services

Maximize operational efficiency while receiving data you can depend on when you trust your ELISA service needs to the experienced scientists at RayBiotech.

Related Covid-19 Products

Patient Samples

Different sample types from COVID-19 diagnosed patients and COVID-19 vaccinated patients, including serum/plasma, PBMCs, dried blood spots, & more.

Covid-19 ELISA Kits

Detect IgG, IgM, and IgA antibodies to SARS-CoV-2 N and S proteins in serum, saliva, and dried blood samples using the indirect ELISA kits.

Covid-19 PCR Kits

RayBiotech's innovative PCR kits allow rapid, convenient detection of SARS-CoV-2 nucleic acids. Our protocols offer unique advantages, such as enabling the researcher to skip laborious RNA extraction, or to avoid PCR machines entirely, and detect the virus by visual color inspection.

Covid-19 Binding Assays

COVID-19 binding assays enable rapid, high throughput, and in vitro screening of potential inhibitors of Spike-receptor complexes that facilitate SARS-CoV-2 viral entry.

References

  1. Astuti I, Ysrafil. Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2): An overview of viral structure and host response. Diabetes Metab Syndr. 2020;14(4):407-412. doi:10.1016/j.dsx.2020.04.020
  2. Hoffmann M, Kleine-Weber H, Schroeder S, et al. SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor. Cell.2020;181(2):271-280.e8. doi:10.1016/j.cell.2020.02.052
  3. Expression of the SARS-CoV-2 cell receptor gene ACE2 in a wide variety of human tissues | Infectious Diseases of Poverty | Full Text. Accessed September 16, 2022. https://idpjournal.biomedcentral.com/articles/10.1186/s40249-020-00662-x
  4. Zhao M. Cytokine storm and immunomodulatory therapy in COVID-19: Role of chloroquine and anti-IL-6 monoclonal antibodies. Int J Antimicrob Agents. 2020;55(6):105982. doi:10.1016/j.ijantimicag.2020.105982
  5. CDC. COVID-19 and Your Health. Centers for Disease Control and Prevention. Published February 11, 2020. Accessed September 16, 2022.https://www.cdc.gov/coronavirus/2019-ncov/symptoms-testing/testing.html