COVID-19 Proteins

The SARS-CoV-2 virus, which is responsible for COVID-19, comprises nearly 30 proteins, including the Spike and Nucleocapsid proteins. RayBiotech offers a comprehensive catalog of recombinant SARS-CoV-2 proteins for all domains and variants of the COVID-19 virus. Other recombinant coronavirus proteins, including SARS-CoV, MERS-CoV, and HCoV-HKU1, are also available for purchase.

Browse All COVID-19 Proteins
SARS-CoV-2_Proteins

Features

The recombinant SARS-CoV-2 proteins recommended applications include ELISA, western blotting, lateral flow, antibody generation, vaccine development, and more. All recombinant proteins have a purity greater than 90% determined by SDS-PAGE under reducing conditions and visualized by Coomassie blue staining. Images are available on the product-specific pages. Multiple expression systems are available, including Human Embryonic Kidney 293 (HEK293) Cells and E.coli.

Learn about the roles SARS-CoV-2 proteins and endogenous proteins play in COVID-19 infection in our post “COVID-19 Biology 101”.

Product Categories

Spike Protein

The spike protein (S-protein) is a structural, transmembrane protein that is displayed on the surface of the viral particle.

Spike Protein Variants

SARS-CoV-2 variants have mutations within the gene encoding for the Spike (S) protein, which facilitates viral entry by binding to host receptors.

Nucleocapsid Protein

The nucleocapsid protein (N-protein) is a structural protein that binds to the coronavirus RNA genome.

Membrane Protein

The membrane protein (M-protein) is the most abundant structural protein of SARS-CoV-2.

Other Coronavirus Proteins

Recombinant SARS, MERS, and HKU1 coronavirus proteins.

Thrombosis Proteins

Inflammation associated with COVID-19 can lead to a type of thrombosis called "disseminated intravascular coagulopathy" (DIC).

Host Receptors

ACE2 is an endogenous receptor that is required for SARS-CoV-2 viral entry. Other host receptors, NRP1, AXL, CD147, GRP-78 also assist.

Popular Recombinant SARS-CoV-2 Proteins

  1. Recombinant SARS-CoV-2, S1 Subunit Protein (RBD)
    Recombinant SARS-CoV-2, S1 Subunit Protein (RBD) Recombinant SARS-CoV-2, S1 Subunit Protein (RBD) with C-terminal His tag, derived from the transfected human HEK293 cells.
    Datasheet
  2. Recombinant SARS-CoV-2 Spike Protein, S1 Subunit
    Recombinant SARS-CoV-2 Spike Protein, S1 Subunit Recombinant SARS-CoV-2 Spike Protein, S1 Subunit derived from E.coli
  3. Recombinant SARS-CoV-2 S1 Subunit Protein (full length)
    Recombinant SARS-CoV-2 S1 Subunit Protein (full length)

    Recombinant SARS-CoV-2 S1 subunit protein with C-terminal His-tag, derived from the transfected human HEK293 cells.

  4. Recombinant SARS-CoV-2 Nucleocapsid Protein
    Recombinant SARS-CoV-2 Nucleocapsid Protein Recombinant SARS-CoV-2 Nucleocapsid Protein with C-terminal His-tag, derived from the transfected human HEK293 cells.
    Datasheet
  5. Recombinant SARS-CoV-2 Nucleocapsid Protein
    Recombinant SARS-CoV-2 Nucleocapsid Protein Recombinant SARS-CoV-2 Nucleocapsid Protein derived from E.coli
  6. Recombinant SARS-CoV-2 Spike Protein, S2 Subunit
    Recombinant SARS-CoV-2 Spike Protein, S2 Subunit Recombinant SARS-CoV-2 Spike Protein, S2 Subunit derived from E.coli

New Products

  1. Recombinant SARS-CoV-2 Omicron Variant B.1.1.529 Nucleocapsid (N) Protein
    Recombinant SARS-CoV-2 Omicron Variant B.1.1.529 Nucleocapsid (N) Protein Recombinant SARS-CoV-2 Omicron Variant B.1.1.529 Nucleocapsid (N), derived from the transfected human HEK293 cells.
  2. Recombinant SARS-CoV-2 Replicase Polyprotein 1a (3C-like Proteinase Nsp5)
    Recombinant SARS-CoV-2 Replicase Polyprotein 1a (3C-like Proteinase Nsp5) Recombinant SARS-CoV-2 replicase polyprotein 1a (3C-like Proteinase Nsp5) derived from E.coli
  3. Recombinant SARS-CoV-2 S1 Subunit Protein (RBD), mutant N331Q, Biotinylated
    Recombinant SARS-CoV-2 S1 Subunit Protein (RBD), mutant N331Q, Biotinylated Biotin-conjugated recombinant SARS-CoV-2 S1 subunit protein (RBD) mutant N331Q with C-terminal His-tag, derived from the transfected human HEK293 cells.
  4. Recombinant SARS-CoV-2 Nucleocapsid Protein, Biotinylated
    Recombinant SARS-CoV-2 Nucleocapsid Protein, Biotinylated Biotin-conjugated recombinant SARS-CoV-2 Nucleocapsid Protein with C-terminal His-tag, derived from the transfected human HEK293 cells.

What customers are saying

It works well for fluorescent labeling and confocal microscopy.

Research Scientist

University of California, Davis

We employed this protein for site-specific glycosylation analysis. It works great.

Research Scientist

University of California, Davis

viral-particle

Featured Service

COVID-19 Pseudovirus Service

RayBiotech's COVID-19 pseudovirus service enables the study of the SARS-CoV-2 virus in cell culture. This service is ideal for screening patient serum for neutralizing antibodies, validating inhibitors of the Spike-ACE2 interaction, and COVID-19 vaccine development.

View Pseudovirus Services

Related Services

Protein Expression and Purification

Comprehensive custom protein service covers every step of production, from gene cloning through protein purification. We can also perform downstream processing like protein desalting, lyophilization, vialing, and labeling.

COVID-19 Antibodies

RayBiotech offers monoclonal and polyclonal antibodies against SARS-CoV-2 (COVID-19) proteins, including the Nucleocapsid protein (N-protein) and multiple domains and variants of the Spike protein (S-protein).

COVID-19 ELISAs

Current testing for the SARS-CoV-2 virus is limited, and compared to RT-qPCR, ELISA is a less complex procedure that uses more affordable and available equipment.