COVID-19 Proteins

The SARS-CoV-2 virus, which is responsible for COVID-19, comprises nearly 30 proteins, including the Spike and Nucleocapsid proteins. RayBiotech offers a comprehensive catalog of recombinant SARS-CoV-2 proteins for all domains and variants of the COVID-19 virus. Other recombinant coronavirus proteins, including SARS-CoV, MERS-CoV, and HCoV-HKU1, are also available for purchase.



The recombinant SARS-CoV-2 proteins recommended applications include ELISA, western blotting, lateral flow, antibody generation, vaccine development, and more. All recombinant proteins have a purity greater than 90% determined by SDS-PAGE under reducing conditions and visualized by Coomassie blue staining. Images are available on the product-specific pages. Multiple expression systems are available, including Human Embryonic Kidney 293 (HEK293) Cells and E.coli.

Learn about the roles SARS-CoV-2 proteins and endogenous proteins play in COVID-19 infection in our post “COVID-19 Biology 101”.

Product Categories

Spike Protein

The spike protein (S-protein) is a structural, transmembrane protein that is displayed on the surface of the viral particle.

Spike Protein Variants

SARS-CoV-2 variants have mutations within the gene encoding for the Spike (S) protein, which facilitates viral entry by binding to host receptors.

Nucleocapsid Protein

The nucleocapsid protein (N-protein) is a structural protein that binds to the coronavirus RNA genome.

Membrane Protein

The membrane protein (M-protein) is the most abundant structural protein of SARS-CoV-2.

Other Coronavirus Proteins

Recombinant SARS, MERS, and HKU1 coronavirus proteins.

Thrombosis Proteins

Inflammation associated with COVID-19 can lead to a type of thrombosis called "disseminated intravascular coagulopathy" (DIC).

Host Receptors

ACE2 is an endogenous receptor that is required for SARS-CoV-2 viral entry. Other host receptors, NRP1, AXL, CD147, GRP-78 also assist.

Popular Recombinant SARS-CoV-2 Proteins

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What customers are saying

It works well for fluorescent labeling and confocal microscopy.

Research Scientist

University of California, Davis

We employed this protein for site-specific glycosylation analysis. It works great.

Research Scientist

University of California, Davis


Featured Service

COVID-19 Pseudovirus Service

RayBiotech's COVID-19 pseudovirus service enables the study of the SARS-CoV-2 virus in cell culture. This service is ideal for screening patient serum for neutralizing antibodies, validating inhibitors of the Spike-ACE2 interaction, and COVID-19 vaccine development.

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