Goat Anti-Human 5-Hydroxymethyluridine

Goat Anti-Human 5-Hydroxymethyluridine

DS-PB-02203
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Antigen Information

Protein Name & Synonyms:
5-Hydroxymethyluridine
Target Species:
  • Human

Antibody Specifications

Applications:
ELISA (dilution: , 1/25000)
Preparation:
Antisera to 5-hydroxymethyluridine were raised by repeated immunisations of goats with highly purified antigen.
Species Reactivity:
Human

Specificity

This product recognizes 5-hydroxymethyluridine, which is created by the oxidation of thymine by ionising radiation or reactive oxygen species. This oxidation causes changes in gene expression, mutations and chromosomal instability all of which play a role in cancer, autoimmune disease and aging. 5-hydroxymethyluridine is a potential biomarker for female breast, colon and rectal cancers, being present at elevated levels, possibly due to impaired DNA repair mechanisms.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Serum - liquid
Format Type:
Serum

Preparation

Antisera to 5-hydroxymethyluridine were raised by repeated immunisations of goats with highly purified antigen.

Immunogen:
5-hydroxymethyluridine
Preservative:
0.09%Sodium Azide (NaN3)

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.