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Antigen Information
Protein Name & Synonyms:
ABCB5
Target Species:
- Human
Antibody Specifications
Applications:
ELISA (dilution: 0.03, 0.1ug/ml), Western Blotting
Concentration:
0.5mg/ml
Host Species:
Goat
Immunogen Sequence:
C-QTQHRNTSKKAQ
Species Reactivity:
Human
This product detects a band of approximately 80kDa in A431cell lysates
Specificity
This product specifically recognizes human ABCB5 (ATP-binding cassette sub-family B member 5), a P-glycoprotein and member of the conserved ABC transporter family, which acts as an energy-dependent efflux transporter for rhodamine.
ABCB5 is primarily expressed by skin progenitor cells and shown to act as a regulator of cell fusion and determinant of membrane potential. Studies have revealed the expression of ABCB5 in human malignant melanoma tumours, and in particular its association with CD133+ stem cell phenotype-expressing cells.
ABCB5 is primarily expressed by skin progenitor cells and shown to act as a regulator of cell fusion and determinant of membrane potential. Studies have revealed the expression of ABCB5 in human malignant melanoma tumours, and in particular its association with CD133+ stem cell phenotype-expressing cells.
Storage/Stability
Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Format
Supplied as:
Purified IgG - liquid
Formulation:
TRIS buffered saline
Format Type:
Purified
Preparation
Antiserum to ABCB5 was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Immunogen:
Peptide sequence C-QTQHRNTSKKAQ from the internal region of ABCB5 (NP_848654.3)
Preservative:
0.02% Sodium Azide (NaN3)
0.5% Bovine Serum Albumin
0.5% Bovine Serum Albumin
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Usage
This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.
