Goat Anti-Human ASS1

Goat Anti-Human ASS1

129-10041
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Antigen Information

Protein Name & Synonyms:
ASS1
Target Species:
  • Human

Antibody Specifications

Applications:
ELISA (dilution: 0.01, 0.03ug/ml), Western Blotting
Concentration:
0.5mg/ml
Host Species:
Goat
Immunogen Sequence:
C-ENPKNQAPPGLYTKTQD
Species Reactivity:
Human

This product detects a band of approximately 45kDa in human kidney cell lysates

Specificity

This product specifically recognizes human ASS1 (Argininosuccinate synthetase 1), an ornithine (urea) cycle enzyme and member of the argininosuccinate synthase family, which catalyzes the penultimate step of the arginine biosynthetic pathway.

Defects in ASS1 genes are responsible for the autosomal recessive disease known as citrullinemia type 1 (CTLN1), characterized by increased levels of urine and serum citrulline, and ammonia intoxication.

This product is reported as suitable for use in immunoprecipitation studies.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG - liquid
Formulation:
TRIS buffered saline
Format Type:
Purified

Preparation

Antiserum to ASS1 was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.

Immunogen:
Peptide sequence C-ENPKNQAPPGLYTKTQD from the internal region of ASS1 (NP_000041.2; NP_446464.1).
Preservative:
0.02% Sodium Azide (NaN3)
0.5% Bovine Serum Albumin

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.