Goat Anti-Human IL-12

Goat Anti-Human IL-12

DS-PB-01085
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Antigen Information

Protein Name & Synonyms:
IL-12
Target Species:
  • Human

Antibody Specifications

Applications:
ELISA (dilution: 0.1, 0.2ug/ml), Functional Assays, Western Blotting
Concentration:
IgG concentration 1.0mg/ml
Preparation:
Antisera to human IL-12 were raised by repeated immunisations of goats with highly purified antigen. Purified IgG prepared by affinity chromatography.
Reconstitution:
Reconstitute with 0.1ml distilled water. For long term storage the addition of 0.09% sodium azide is recommended. N.B For functional studies do not add azide.
Species Reactivity:
Human

Specificity

This product is specific for human IL-12 (Interleukin-12), a pleiotropic 75kDa heterodimeric glycoprotein, consisting of disulfide-linked IL-12A (p35) and IL-12B (p40) subunits, which signals through the high affinity IL-12 receptor.

IL-12 is produced primarily by antigen presenting cells and was originally called cytotoxic lymphocyte maturation factor (CLMF), identified by its ability to induce cytotoxic effector cells, in synergy with IL-2. IL-12 is an important factor in the T helper cell (Th1) immune response, promotes the development and activity of activated T cells and natural killer cells (NK), induces IFN-gamma production, and enhances resistance against invading pathogens.

Storage/Stability

Prior to reconstitution store at +4 °C.
After reconstitution store at -20 °C.
This product should be stored undiluted.
Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 12 months after receipt.

Format

Supplied as:
Purified IgG - lyophilized
Formulation:
Phosphate buffered saline
Reconstitution:
Reconstitute with 0.1ml distilled water. For long term storage the addition of 0.09% sodium azide is recommended. N.B For functional studies do not add azide.
Format Type:
Purified

Preparation

Antisera to human IL-12 were raised by repeated immunisations of goats with highly purified antigen. Purified IgG prepared by affinity chromatography.

Immunogen:
Recombinant human IL-12
Preservative:
None present

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.