Goat Anti-Human RXR alpha

Goat Anti-Human RXR alpha

DS-PB-01749
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Antigen Information

Protein Name & Synonyms:
RXR alpha
Target Species:
  • Human

Antibody Specifications

Applications:
ELISA (dilution: 0.5, 3ug/ml), Western Blotting
Concentration:
IgG concentration 0.5 mg/ml
Preparation:
Antisera to human RXR alpha were raised by repeated immunisations of goats with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Species Reactivity:
Human

This product detects a band of approximately 55kDa in human epidermoid carcinoma A431 lysates. A minimum incubation time of 1 hour is recommended with this antibody.

Specificity

This product detects an epitope within the internal region of retinoid X receptor alpha (RXR alpha). RXR alpha is a 54kD member of the steroid/ thyroid receptor superfamily of transcriptional regulators, and is a nuclear receptor that mediates the biological effects of retinoids through its involvement in retinoic acid-mediated gene activation. RXR alpha regulates gene transcription by recruiting coactivators or corepressors to their promoter sequences.

RXRs play important roles in multiple signalling pathways, including cell growth, differentiation, homeostasis, metabolism, and development.

This product does not cross-react with either RXR beta or gamma.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.

This product should be stored undiluted.

Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG - liquid
Formulation:
TRIS buffered saline
Format Type:
Purified

Preparation

Antisera to human RXR alpha were raised by repeated immunisations of goats with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.

Immunogen:
Peptide sequence CQVNSSLTSPTGRGSM corresponding to the internal region of RXR alpha (NP_002948).
Preservative:
0.02%Sodium Azide
0.5%Bovine Serum Albumin

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.