Goat Anti-Human Synuclein alpha

Goat Anti-Human Synuclein alpha

DS-PB-00115
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Antigen Information

Protein Name & Synonyms:
Synuclein alpha
Target Species:
  • Human

Antibody Specifications

Applications:
ELISA (dilution: , 1/300), Immunohistology - Paraffin
Preparation:
Antisera to a-synuclein were raised by repeated immunisation of goats with highly purified antigen.
Species Reactivity:
Human
Immunohistology:
This product does not require protein digestion pre-treatment of paraffin sections. This product does not require antigen retrieval using heat treatment prior to staining of paraffin sections.

Specificity

This product recognizes human alpha-synuclein.

The alpha-synuclein gene, located on chromosome 4, has been linked to early onset autosomal dominant Parkinson's disease.

The protein is abundant in the nervous system, and is known to be the precursor of the non-beta amyloid component protein (NACP) of Alzheimer's disease. Alpha-synuclein has also been found to be associated with other neurodegenerative diseases such as multiple system atrophy and dementia with Lewy's bodies.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.

This product should be stored undiluted.

Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Serum - liquid
Format Type:
Serum

Preparation

Antisera to a-synuclein were raised by repeated immunisation of goats with highly purified antigen.

Immunogen:
Synthetic peptide corresponding to amino acids 116-131 of the C-terminus of a synuclein
Preservative:
0.09%Sodium Azide

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.