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Antigen Information
Protein Name & Synonyms:
CDw198
Target Species:
- Mouse
Antibody Specifications
Applications:
ELISA (dilution: , 1/1000), Immunohistology - Paraffin, Western Blotting
Concentration:
1.0mg/ml
Host Species:
Goat
Immunogen Sequence:
PNVTMTDYYPDFFTAPCDAEFLLRGSM
Species Reactivity:
Mouse
Specificity
This product specifically recognizes mouse CDw198, otherwise known as CCR8 (C-C chemokine receptor type 8), a transmembrane glycoprotein and member of the G-protein coupled receptor 1 family, which acts a high-affinity receptor for the chemokine I-309 (CCL1), implicated in the regulation of monocyte chemotaxis and thymocyte apoptosis.
CDw198 is constitutively expressed by monocytes, preferentially expressed on Th2 (type 2 helper T) cells, and acts as a co-receptor with CD4 for HIV1 infection.
CDw198 is constitutively expressed by monocytes, preferentially expressed on Th2 (type 2 helper T) cells, and acts as a co-receptor with CD4 for HIV1 infection.
Storage/Stability
Store at -20 °C only.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Format
Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified
Preparation
Antiserum to mouse CDw198 was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Immunogen:
Synthetic peptide PNVTMTDYYPDFFTAPCDAEFLLRGSM corresponding to amino acids 7-33 of mouse CDw198.
Preservative:
0.09% Sodium Azide (NaN3)
0.1% Bovine Serum Albumin
0.1% Bovine Serum Albumin
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Usage
This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.
