Goat Anti-Rotovirus

Goat Anti-Rotovirus

DS-PB-01743
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Antigen Information

Protein Name & Synonyms:
Rotovirus
Target Species:
  • Viral

Antibody Specifications

Applications:
Immunofluorescence
Concentration:
4.0 mg/ml
Species Reactivity:
Viral

Specificity

This product reacts with rotavirus and is specific for ICPs and late structural (virion) antigens. It has been reported to exhibit 90% cross reactivity with human rotavirus and does not react with HEp-2 cells or WI-38 cells in immunofluorescence.

Rotavirus is a virus that infects the bowels and is the most common cause of gastroenteritis in infants. 7 major groups have currently been identified, 3 of which infect humans (groups A, B and C). Its genome consists of 11 segments of double stranded RNA held in the inner core of the three layered, icosahedral virion particle. The genome codes for 6 virus proteins (VP1,2,3,4,6,7) and 6 non-structural proteins (NSP1-6). Outer capsid proteins are VP4 and VP7, inner capsid -VP6 and core -VP2. The immunity acquired from exposure to rotavirus appears to be type specific following initial infection; therefore, multiple serotypes of rotavirus mean multiple opportunities for infection.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Ig fraction - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified

Preparation

Immunogen:
Nebraska calf diarrhea virus.
Preservative:
0.09%Sodium Azide (NaN3)

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.