Hamster Anti-Mouse CD178 [+FITC]

Hamster Anti-Mouse CD178 [+FITC] (0.1 mg)

$412.00
129-10108
+

Antigen Information

Protein Name & Synonyms:
CD178
Target Species:
  • Mouse

Antibody Specifications

Applications:
Flow Cytometry
Concentration:
0.1mg/ml
Host Species:
Hamster
Species Reactivity:
Mouse, Rat

Specificity

This product recognizes both mouse and rat CD178, otherwise known as Fas Ligand/ CD95L, a 40kDa type II transmembrane glycoprotein and member of the TNF/NGF superfamily, expressed by activated T cells and NK cells, which can be induced on a variety of cells by radiation, heat shock, chemotherapeutic agents and viral infection.

CD178 acts as a key effector of cytotoxicity and in the regulation of immune responses. The binding of CD178 to its receptor CD95 (Fas), induces Fas-mediated apoptosis of target cells, and may be involved in the induction of peripheral tolerance and neutrophil chemotaxis. The binding of decoy receptor 3 (DcR3) to CD178 has been shown to inhibit CD178-mediated apoptosis.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid
Formulation:
Phosphate buffered saline

Preparation

Immunogen:
B6 mouse FasL/BHK cells
Preservative:
0.09% Sodium Azide (NaN3)
1% Bovine Serum Albumin

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.