Hamster Anti-Mouse CD178, Low Endotoxin

Hamster Anti-Mouse CD178, Low Endotoxin (0.5 mg)

$715.00
129-10109
+

Antigen Information

Protein Name & Synonyms:
CD178
Target Species:
  • Mouse

Antibody Specifications

Applications:
Flow Cytometry, Functional Assays
Concentration:
1.0mg/ml
Host Species:
Hamster
Species Reactivity:
Mouse, Rat

Specificity

This product recognizes both mouse and rat CD178, otherwise known as Fas Ligand/ CD95L, a 40kDa type II transmembrane glycoprotein and member of the TNF/NGF superfamily, expressed by activated T cells and NK cells, which can be induced on a variety of cells by radiation, heat shock, chemotherapeutic agents and viral infection.

CD178 acts as a key effector of cytotoxicity and in the regulation of immune responses. The binding of CD178 to its receptor CD95 (Fas), induces Fas-mediated apoptosis of target cells, and may be involved in the induction of peripheral tolerance and neutrophil chemotaxis. The binding of decoy receptor 3 (DcR3) to CD178 has been shown to inhibit CD178-mediated apoptosis.

This product is reported to block CD178/CD95 induced apoptosis.

Storage/Stability

Store at -20 °C only.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Quality Control (Contaminants):
<0.01EU/ug
Format Type:
Low Endotoxin

Preparation

Immunogen:
B6 mouse FasL/BHK cells
Preservative:
None present

No posts found

Write A Review
U.S. Non-U.S.

Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.