Hamster Anti-Mouse CD278

Hamster Anti-Mouse CD278 (0.25 mg)

$488.00
129-10138
+

Antigen Information

Protein Name & Synonyms:
CD278
Target Species:
  • Mouse

Antibody Specifications

Applications:
Immunohistology - Frozen, Flow Cytometry, Immunoprecipitation
Concentration:
0.5mg/ml
Host Species:
Hamster
Species Reactivity:
Mouse, Human, Pig, Rat

Specificity

This product recognizes CD278, also known as Inducible T cell costimulator or ICOS, a CD28-superfamily costimulatory molecule. It is expressed on activated T cells and resting memory T cells. It enhances all the basic T cell responses to a foreign antigen, namely proliferation, secretion of lymphokines and up-regulation of molecules that mediate cell-cell interaction. It is essential for the efficient interaction between B and T cells and is involved in antibody responses to T cell dependent antigens. It up-regulates the synthesis of interleukin-10, but not interleukin-2 and prevents the apoptosis of pre-activated T cells. This antibody has been reported to costimulate T cell activation and proliferation in vitro.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified

Preparation

Immunogen:
Mouse T cell This product class='ty-product-feature'>
Preservative:
0.09% Sodium Azide (NaN3)

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.