Hamster Anti-Mouse CD3 [+Biotin]

Hamster Anti-Mouse CD3 [+Biotin] (0.1 mg)
CODE:  DS-PB-02359

Antigen Information

Protein Name & Synonyms:
CD3
Target Species:
  • Mouse

Antibody Specifications

Applications:
Flow Cytometry
Concentration:
IgG concentration 0.5mg/ml
Species Reactivity:
Mouse

Specificity

This product detects CD3 epsilon (CD3e), a 20kDa transmembrane protein also known as CD3 or T3. CD3e is a member of the CD3 complex which consists of four subunits, gamma, delta, epsilon and zeta, and these are associated to the T cell receptor (TCR). TCR plays a critical role in T cell development and function, and is responsible for ligand recognition. It interacts non-covalently with the CD3 dimers delta/epsilon, gamma/epsilon and zeta/zeta which transduce signals from the TCR into the cell.

CD3e is primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation.

The antibody is useful for in vitro blocking and activation assays, as well as apoptosis induction and in vitro T cell depletions.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG conjugated to Biotin - liquid
Formulation:
Phosphate buffered saline

Preparation

Immunogen:
H-2Kb - specific mouse cytoxic T lymphocyte This product class='ty-product-feature'>
Preservative:
0.09%Sodium Azide (NaN3)
1%Bovine Serum Albumin