Human epididymis protein 4, belongs to the whey acidic protein four-disulfide core (WFDC) protein family and has suspected trypsin inhibitor properties. HE4 can be detected in serum, and is highly expressed in ovarian cancer tissues, but not in adjacent tissues, normal tissues, or benign tumor tissue. Ovarian cancer has the third highest incidence rate out of all female genital system cancers, but the mortality rate is the highest. HE4 has been highly reported in the literature as a high sensitivity tumor marker that is relevant in the early diagnosis of ovarian cancer, especially at the initial stage of symptom presentation. Thus, the detection or monitoring of HE4 is helpful for the diagnosis of an evaluation of curative treatment for malignant ovarian tumors[1-4].
The kit contains the following components. The entire kit can be used for 96 HE4 level measurements.
|HE4 ELISA Plate||One 96-well plate|
|Plate Sealing Film||2 films|
|HE4 Enzyme Conjugate||One 10mL bottle|
|HE4 Calibration Vial||Five 0.5mL vials (S1-S6)*|
|Wash Concentrate 20X||One 20mL bottle|
|Coloring Solution||One 1mL bottle|
|Stop Solution||One 7mL bottle|
|Instruction Manual||One copy|
Note: The components of different lot numbers are not interchangeably.
*The HE4 Calibration Vials S1-S6 contain 40pmol/L, 80pmol/L, 160pmol/L, 320pmol/L, 640pmol/L, and 1300pmol/L of HE4 recombinant antigen, respectively.
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*Not approved for diagnostic or therapeutic use in the USA