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Inflammation Arrays

RayBiotech offers 11 different Inflammation Antibody Arrays for detecting up to 40 inflammatory factors in Human, Mouse, and Rat species. See the below product listings for more information.

Human Inflammation Arrays

Human Inflammation Array Q1

Human Inflammation Array Q1

(QAH-INF-1)

Quantibody Arrays - Quantitative, Sandwich-Based, Glass Slide Antibody Arrays

Detects 10 Human Inflammatory Factors:

IFN-gamma, IL-1 alpha (IL-1 F1), IL-1 beta (IL-1 F2), IL-10, IL-13, IL-4, IL-6, IL-8 (CXCL8), MCP-1 (CCL2), TNF alpha

PDFManualOverviewQuantibody Overview

Human Inflammation Array Q1

Human Inflammation Array Q3

(QAH-INF-3)

Quantibody Arrays - Quantitative, Sandwich-Based, Glass Slide Antibody Arrays

Detects 40 Human Inflammatory Factors:

BLC (CXCL13), Eotaxin-1 (CCL11), Eotaxin-2 (MPIF-2/CCL24), GCSF, GM-CSF, I-309 (TCA-3/CCL1), ICAM-1 (CD54), IFN-gamma, IL-1 alpha (IL-1 F1), IL-1 beta (IL-1 F2), IL-1 ra (IL-1 F3), IL-2, IL-4, IL-5, IL-6, IL-6 R, IL-7, IL-8 (CXCL8), IL-10, IL-11, IL-12 p40, IL-12 p70, IL-13, IL-15, IL-16, IL-17A, MCP-1 (CCL2), M-CSF, MIG (CXCL9), MIP-1 alpha (CCL3), MIP-1 beta (CCL4), MIP-1 delta (CCL15), PDGF-BB, RANTES (CCL5), TIMP-1, TIMP-2, TNF alpha, TNF beta (TNFSF1B), TNF RI (TNFRSF1A), TNF RII (TNFRSF1B)

PDFManualOverviewQuantibody Overview

Human Inflammation Array C1

Human Inflammation Array C1

(AAH-INF-1)

C-Series Arrays - Semi-Quantitative, Sandwich-Based, Membrane Antibody Arrays

Detects 20 Human Inflammatory Factors:

Eotaxin-1 (CCL11), Eotaxin-2 (MPIF-2/CCL24), GCSF, GM-CSF, IFN-gamma, IL-1 alpha (IL-1 F1), IL-1 beta (IL-1 F2), IL-2, IL-3, IL-4, IL-6, IL-7, IL-8 (CXCL8), IL-10, IL-11, IL-12 p40, IL-12 p70, IL-13, I-309 (TCA-3/CCL1), TIMP-2

PDFManualOverviewC-Series Overview

Human Inflammation Array C2

Human Inflammation Array C2

(AAH-INF-2)

C-Series Arrays - Semi-Quantitative, Sandwich-Based, Membrane Antibody Arrays

Detects 20 Human Inflammatory Factors:

ICAM-1 (CD54), IL-6 R, IL-15, IL-16, IL-17A, IP-10 (CXCL10), MCP-1 (CCL2), MCP-2 (CCL8), M-CSF, MIG (CXCL9), MIP-1 alpha (CCL3), MIP-1 beta (CCL4), MIP-1 delta (CCL15), RANTES (CCL5), TGF beta 1, TNF alpha, TNF beta (TNFSF1B), TNF RI (TNFRSF1A), TNF RII (TNFRSF1B), PDGF-BB

PDFManualOverviewC-Series Overview

Human Inflammation Array C3

Human Inflammation Array C3

(AAH-INF-3)

C-Series Arrays - Semi-Quantitative, Sandwich-Based, Membrane Antibody Arrays

Detects 40 Human Inflammatory Factors:

Eotaxin-1 (CCL11), Eotaxin-2 (MPIF-2/CCL24), GCSF, GM-CSF, ICAM-1 (CD54), IFN-gamma, I-309 (TCA-3/CCL1), IL-1 alpha (IL-1 F1), IL-1 beta (IL-1 F2), IL-2, IL-3, IL-4, IL-6, IL-6 R, IL-7, IL-8 (CXCL8), IL-10, IL-11, IL-12 p40, IL-12 p70, IL-13, IL-15, IL-16, IL-17A, IP-10 (CXCL10), MCP-1 (CCL2), MCP-2 (CCL8), M-CSF, MIG (CXCL9), MIP-1 alpha (CCL3), MIP-1 beta (CCL4), MIP-1 delta (CCL15), RANTES (CCL5), TGF beta 1, TNF alpha, TNF beta (TNFSF1B), TNF RI (TNFRSF1A), TNF RII (TNFRSF1B), PDGF-BB, TIMP-2

PDFManualOverviewC-Series Overview

Human Inflammation Array G3

Human Inflammation Array G3

(AAH-INF-G3)

G-Series Arrays - Semi-Quantitative, Sandwich-Based, Glass Slide Antibody Arrays

Detects 40 Human Inflammatory Factors:

Eotaxin-1 (CCL11), Eotaxin-2 (MPIF-2/CCL24), GCSF, GM-CSF, ICAM-1 (CD54), IFN-gamma, I-309 (TCA-3/CCL1), IL-1 alpha (IL-1 F1), IL-1 beta (IL-1 F2), IL-2, IL-3, IL-4, IL-6, IL-6 R, IL-7, IL-8 (CXCL8), IL-10, IL-11, IL-12 p40, IL-12 p70, IL-13, IL-15, IL-16, IL-17A, IP-10 (CXCL10), MCP-1 (CCL2), MCP-2 (CCL8), M-CSF, MIG (CXCL9), MIP-1 alpha (CCL3), MIP-1 beta (CCL4), MIP-1 delta (CCL15), RANTES (CCL5), TGF beta 1, TNF alpha, TNF beta (TNFSF1B), TNF RI (TNFRSF1A), TNF RII (TNFRSF1B), PDGF-BB, TIMP-2

PDFManualOverviewG-Series Overview

Mouse Inflammation Arrays

Mouse Inflammation Array Q1

Mouse Inflammation Array Q1

(QAM-INF-1)

Quantibody Arrays - Quantitative, Sandwich-Based, Glass Slide Antibody Arrays

Detects 40 Mouse Inflammatory Factors:

BLC (CXCL13), CD30 Ligand (TNFSF8), Eotaxin-1 (CCL11), Eotaxin-2 (MPIF-2/CCL24), Fas Ligand (TNFSF6), GCSF, GM-CSF, I-309 (TCA-3/CCL1), ICAM-1 (CD54), IFN-gamma, IL-1 alpha (IL-1 F1), IL-1 beta (IL-1 F2), IL-10, IL-12 p70, IL-13, IL-15, IL-17A, IL-2, IL-21, IL-3, IL-4, IL-5, IL-6, IL-7, KC (CXCL1), Leptin, LIX, MCP-1 (CCL2), MCP-5, M-CSF, MIG (CXCL9), MIP-1 alpha (CCL3), MIP-1 gamma, Platelet Factor 4 (CXCL4), RANTES (CCL5), TARC (CCL17), TIMP-1, TNF alpha, TNF RI (TNFRSF1A), TNF RII (TNFRSF1B)

PDFManualOverviewQuantibody Overview

Mouse Inflammation Array C1

Mouse Inflammation Array C1

(AAM-INF-1)

C-Series Arrays - Semi-Quantitative, Sandwich-Based, Membrane Antibody Arrays

Detects 40 Mouse Inflammatory Factors:

BLC (CXCL13), CD30 Ligand (TNFSF8), Eotaxin-1 (CCL11), Eotaxin-2 (MPIF-2/CCL24), Fas Ligand (TNFSF6), Fractalkine (CX3CL1), GCSF, GM-CSF, IFN-gamma, IL-1 alpha (IL-1 F1), IL-1 beta (IL-1 F2), IL-2, IL-3, IL-4, IL-6, IL-9, IL-10, IL-12 p40/p70, IL-12 p70, IL-13, IL-17A, I-TAC (CXCL11), KC (CXCL1), Leptin, LIX, Lymphotactin (XCL1), MCP-1 (CCL2), M-CSF, MIG (CXCL9), MIP-1 alpha (CCL3), MIP-1 gamma, RANTES (CCL5), SDF-1 alpha (CXCL12 alpha), I-309 (TCA-3/CCL1), TECK (CCL25), TIMP-1, TIMP-2, TNF alpha, TNF RI (TNFRSF1A), TNF RII (TNFRSF1B)

PDFManualOverviewC-Series Overview

Mouse Inflammation Array G1

Mouse Inflammation Array G1

(AAM-INF-G3)

G-Series Arrays - Semi-Quantitative, Sandwich-Based, Glass Slide Antibody Arrays

Detects 40 Mouse Growth Factors:

BLC (CXCL13), CD30 Ligand (TNFSF8), Eotaxin-1 (CCL11), Eotaxin-2 (MPIF-2/CCL24), Fas Ligand (TNFSF6), Fractalkine (CX3CL1), GCSF, GM-CSF, IFN-gamma, IL-1 alpha (IL-1 F1), IL-1 beta (IL-1 F2), IL-2, IL-3, IL-4, IL-6, IL-9, IL-10, IL-12 p40/p70, IL-12 p70, IL-13, IL-17A, I-TAC (CXCL11), KC (CXCL1), Leptin, LIX, Lymphotactin (XCL1), MCP-1 (CCL2), M-CSF, MIG (CXCL9), MIP-1 alpha (CCL3), MIP-1 gamma, RANTES (CCL5), SDF-1 alpha (CXCL12 alpha), I-309 (TCA-3/CCL1), TECK (CCL25), TIMP-1, TIMP-2, TNF alpha, TNF RI (TNFRSF1A), TNF RII (TNFRSF1B)

PDFManualOverviewG-Series Overview

Rat Inflammation Arrays

Rat Inflammation Array Q1

Rat Inflammation Array Q1

(QAR-INF-1)

Quantibody Arrays - Quantitative, Sandwich-Based, Glass Slide Antibody Arrays

Detects 10 Rat Inflammatory Factors:

IFN-gamma, IL-1 alpha (IL-1 F1), IL-1 beta (IL-1 F2), IL-2, IL-4, IL-6, IL-10, IL-13, MCP-1 (CCL2), TNF alpha

PDFManualOverviewQuantibody Overview

Array Features

  • Quantitative or Semi-Quantitative levels of up to 40 Inflammatory Factors are detected simultaneously
  • No need to perform individual immunoprecipitations or Western Blot
  • Reliable results with wide range of cell lines
  • High specificity, sensitivity and reproducibility
  • Membrane formats - No special equipment required
  • Glass slide formats - Fluorescent laser scanner is needed*
  • Many choices: chemiluminescence or fluorescence detection system; Membrane or glass chip

*Click here for a list of compatible laser scanners. Raybiotech now offers free glass slide scanning and data extraction services (click to learn more!).

How It Works

The principle of how an antibody array works

References

  1. Zhai Y, Zhong Z, Chen C-YA, Xia Z, Song L, Blackburn MR, Shyu A-B. Coordinated Changes in mRNA Turnover, Translation, and RNA Processing Bodies in Bronchial Epithelial Cells following Inflammatory Stimulation. Mol Cell Biol. 2008; 28(24):7414?7426.
    Species: Human
    Sample Type: Conditioned Media

  2. Modulation of Cytokine Release and Gene Expression by the Immunosuppressive Domain of gp41 of HIV-1
    Species: Human
    Sample Type: Conditioned Media

  3. Zeng Q., Chen W. The functional behavior of a macrophage/fibroblast co-culture model derived from normal and diabetic mice with a marine gelatineoxidized alginate hydrogel. Biomaterials 31 (2010) 5772-5781
    Species: Mouse
    Sample Type: Conditioned Media

  4. Morin C., Roumegous A., Carpenter G., Barbier-Chassfiere V., et al. Modulation of Inflammation by Cicaderma Ointment Accelerates Skin Wound Healing. JPET October 2012 vol. 343 no. 1 115-124
    Species: Mouse
    Sample Type: Mouse Skin Homogenates

  5. The functional behavior of a macrophage/fibroblast co-culture model derived from normal and diabetic mice with a marine gelatin oxidized alginate hydrogel
    Species: Mouse

  6. Chia C., Kumari U., Casey P. Breast cancer cell invasion mediated by Galpha12 signaling involves expression of interleukins-6 and -8, and matrix metalloproteinase-2. Journal of Molecular Signaling 2014, 9:6 doi:10.1186/1750-2187-9-6
    Species: Human
    Sample Type: Conditioned Media

  7. Granulocytosis and thrombocytosis in renal cell carcinoma: a pro-inflammatory cytokine response originating in the tumour
    Species: Human

  8. Schriener B, Voss J, Wischhusen J, Dombrowski Y, et al. Expressin of toll-like receptors by human muscle cells in vitro and in vivo: TLR3 is highly expressed in inflammatory and HIV myopathies, mediates IL-8 release and up-regulation of NKG2D ligands. FASEB J. 2005;19(13):U645-U666.
    Species: Human
    Sample Type: Conditioned Media

  9. Nakamura Y, Nawata M, Wakitani S. Expression Profiles and Functional Analyses of Wnt-Related Genes in Human Joint Disorders. Am J Pathol. Jul 2005; 167(1): 97?105.
    Species: Human
    Sample Type: Conditioned Media

  10. Fernandez A M, Fernandez S, Carrero P, Garcia-Garcia M, Torres-Aleman I. Calcineurin in Reactive Astrocytes Plays a Key Role in the Interplay between Proinflammatory and Anti-Inflammatory Signals.J Neuroscience.2007;27(33):8745?8756
    Species: Human
    Sample Type: Cell lysate

  11. Young LR, Borchers MT, Allen HL, Gibbons RS, McCormack FX. Lung-Restricted Macrophage Activation in the Pearl Mouse Model of Hermansky-Pudlak Syndrome. J Immunol. 2006;176:4361?4368.
    Species: Mouse
    Sample Type: BAL Fluid

  12. Wu Z., Chen X., Liu F., Chen W., Wu P., Wieschhaus A., Chishti A., Roche P., Chen W., Lin TJ. Calpain-1 Contributes to IgE-Mediated Mast Cell Activation. The Journal of Immunology April 23, 2014 1301677. doi: 10.4049/? [Epub ahead of print]
    Species: Mouse
    Sample Type: Cell free supernates from Bone-Marrow Mast cells

  13. Ke, F., Zhang, L. et al. Autocrine IL-6 drives skin-derived mesenchymal stem cell trafficking via regulating voltage-gated Ca2+ channels. Stem Cells 2014. Epub Ahead of Print. DOI: 10.1002/stem.1763
    Species: Mouse
    Sample Type: Conditioned Media

  14. Matsunaga K, Yanagisawa S, Ichikawa T, Ueshima K, et al. Airway cytokine expression measured by means of protein array in exhaled breath condensate: Correlation with physiologic properties in asthmatic patients. J Allergy Clin Immunol. 2006; 188:84-90.
    Species: Human

  15. Lin PW, Simon PO, Gewirtz AT, Neish AS, et al. Paneth Cell Cryptdins Act in Vitro as Apical Paracrine Regulators of the Innate Inflammatory Response. J Biol Chem. 2004;279(19):19902-19907.
    Species: Human
    Sample Type: Conditioned Media

  16. Fukuda EY, Lad SP, Mikolon DP, Iacobelli-Martinez M, Li E. Activation of Lipid Metabolism Contributes to Interleukin-8 Production during Chlamydia trachomatis Infection of Cervical Epithelial Cells. Infect Immunity. 2005;73(7):4017-4024.
    Species: Human
    Sample Type: Conditioned Media

  17. Miyoshi N, Oubrahim H, Chock PB, Stadtman ER. Age-dependent cell death and the role of ATP in hydrogen peroxide-induced apoptosis and necrosis. PNAS. 2006;103(6):1727?1731.
    Species: Human
    Sample Type: Conditioned Media

  18. Trinidad AG, de la Puerta ML, Fern?ndez N, Bay?n Y, Crespo MS, Alonso A. Coupling of C3bi to IgG inhibits the tyrosine phosphorylation signaling cascade downstream Syk and reduces cytokine induction in monocytes. J Leukoc.Biol. 2006;79:1073-1082.
    Species: Human
    Sample Type: Conditioned Media

  19. Shiraki Y, Ishibashi Y, Hiruma M, Nishikawa A, Ikeda S. Cytokine secretion profiles of human keratinocytes during Thrichophyton tonsurans and Arthroderma benhamiae infections. J Med Microbiol 2006; 55: 1175-1185.
    Species: Human
    Sample Type: Conditioned Media

  20. Shoji J, Inada N, Sawa M. Antibody Array-Generated Cytokine Profile of Tears of Patients with Vernal Keratoconjunctivitis or Giant Papillary Conjunctivitis. Jpn J Ophthalmol. 2006;50:195-204.
    Species: Human

  21. Fierro NA, Pedraza-Alva G, Rosenstein Y. TCR-Dependent Cell Response is Modulated by the Timing of CD43 Engagement. The Journal of Immunology June 15, 2006 vol. 176 no. 12 7346-7353
    Species: Human
    Sample Type: Conditioned Media

  22. Said NA, Najwer I, Socha MJ, Fulton DJ, Mok SC, Motamed K. SPARC Inhibits LPA-Mediated Mesothelial-Ovarian Cancer Cell Crosstalk. Neoplasia. 2007; 9(1):23?35.
    Species: Human
    Sample Type: Conditioned Media

  23. Cebalo L, Markotic A. Chemokine Production Predominates in Human Monocytes Infected with Tula Virus. Viral Immunol. 2007;20:206?213.
    Species: Human
    Sample Type: Conditioned Media

  24. Ichikawa T,Matsunaga K,Minakata Y, Yanagisawa S, Ueshima K ,et al.Possible Impact of Salivary Infl uence on Cytokine Analysis in Exhaled Breath Condensate. Anal Chem Insights. 2007:2 85?92
    Species: Human

  25. Pyrc K, Bijl A , Dijkman R, Jebbink M, Snoek M, et al. HCoV-NL63 induces interleukin-6 and interleukin-8 expression. In Dissertation by Pyrc KA. Virus discovery and human coronavirus NL63. University of Amsterdam. 2007;121?132.
    Species: human
    Sample Type: Conditioned Media

  26. Long D, Blake S, Song X, Lark M, Loeser R. Human articular chondrocytes produce IL-7 and respond to IL-7 with increased production of matrix metalloproteinase-13. Arthritis Res Ther. 2008;10:R23 doi:10.1186/ar2376
    Species: Human
    Sample Type: Conditioned Media

  27. Matsunaga K,Yanagisawa S,Ichikawa T, Akamatsu K, Koarai A, et al. Molecular Mechanism of the Additive Effects of Leukotriene Modifier in Asthmatic Patients Receiving Steroid Therapy. Allergol Int. 2009;58:89?96.
    Species: Human

  28. Vesey DA, Suen JY, Seow V, et al. PAR2-induced inflammatory responses in human kidney tubular epithelial cells. Am J Physiol Renal Physiol. 2013 Mar 15;304(6):F737-F750.
    Species: Human
    Sample Type: Conditioned Media

  29. PAR2-induced inflammatory responses in human kidney tubular epithelial cells
    Species: Human
    Sample Type: kidney tubular epithelial Conditioned Media

  30. Ichikawa T., Sugiura H., Koarai A., Minakata Y., Kikuchi T., Morishita Y., et al. TLR3 Activation Augments Matrix Metalloproteinase Production through Reactive Nitrogen Species Generation in Human Lung Fibroblasts. The Journal of Immunology April 23, 2014 1302919 [Epub Ahead of Print]
    Species: Human
    Sample Type: Human Fetal Lung Fibroblasts (HFL-1) and U2-OS Conditioned Media

  31. He Y., Liu S., Leone S., Newburg DS. Human colostrum oligosaccharides modulate major immunologic pathways of immature human intestine. Mucosal Immunology, 2014, Published online, April 2. doi: 10.1038/mi.2014.20
    Species: Human
    Sample Type: Tissue Homogenate

  32. Sugitharini V., et al. TLR-mediated inflammatory response to neonatal pathogens and co-infection in neonatal immune cells. Cytokine 69 (2014) 211?217. http://dx.doi.org/10.1016/j.cyto.2014.06.003
    Species: Human
    Sample Type: Conditioned Media

  33. B?rub? J, Roussel L, Nattagh L, Rousseau S. Loss of Cystic Fibrosis Transmembrane conductance Regulator (CFTR) function enhances p38 and ERK MAPKs activation increasing IL-6 synthesis in airway epithelial cells exposed to Pseudomonas aeruginosa. J Biol Chem. 2010;285:22299?22307. doi:10.1074/jbc.M109.098566
    Species: Human

  34. Ide T, Hirase T, Hazuku A,Ikeda Y, Node K. Angiotensin II Increases Expression of IP-10 and the Renin-Angiotensin System in Endothelial Cells. Hypertens Res. 2008;31:1257?1267. doi:10.1291/hypres.31.1257
    Species: Human
    Sample Type: Conditioned Media

  35. McGovern NN, Cowburn AS, Porter L, Walmsley SR, Thompson AAR, et al. Hypoxia Selectively Inhibits Respiratory Burst Activity and Killing of Staphylococcus aureus in Human Neutrophils. J Immunol. 2011;186:453?463.
    Species: Human
    Sample Type: Conditioned Media

  36. Matsunaga K, Ichikawa T, Yanagisawa S, Akamatsu K, Koarai A, et al.Clinical Application of Exhaled Breath Condensate Analysis in Asthma: Prediction of FEV 1 Improvement by Steroid Therapy. Respiration. 2009;78:393?398.
    Species: Human

  37. Rowley A, Baker S, Shulman S, Garcia F, Guzman-Cottrill J, Detection of Antigen in Bronchial Epithelium and Macrophages in Acute Kawasaki Disease by Use of Synthetic Antibody. J Infect Dis. 2004;190:856-865.
    Species: Human
    Sample Type: Tissue Homogenate

  38. Velsko I., Chukkapalli S., Rivera M., Lee J., Chen H., Zhenge D., et al. Active Invasion of Oral and Aortic Tissues by Porphyromonas gingivalis in Mice Causally Links Periodontitis and Atherosclerosis. PLOS One (2014)
    Species: Mouse
    Sample Type: Serum

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