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Discovery in the Post-Genomic Age

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Month: April 2021

The SARS-CoV-2 Life Cycle
April 15, 2021September 7, 2021 Comments 0 Feedbacks on “The SARS-CoV-2 Life Cycle”COVID-19 Brianne Petritis, PhD

The SARS-CoV-2 Life Cycle

Like other coronaviruses, the genome of SARS-CoV-2 contains ten or more open reading frames (ORFs) encoding some 29 proteins. Roughly two thirds of the viral RNA are contained within the first two, called ORF1a and ORF1b. [1] These are translated into two large non-structural polypeptides (NSPS) that are then cleaved…

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