Protein Name & Synonyms:
Flow Cytometry, Functional Assays, Immunofluorescence, Western Blotting
IgG concentration 1.0 mg/ml
This product is specific for bovine CD335, also known as NKp46 and Natural cytotoxicity triggering receptor 1.
CD335 is a type I transmembrane protein, with two extracellular C2-type immunoglobulin-like domains, which functions as an activating receptor.
CD335 is expressed by human natural killer cells (Sivori, S. et al.). The bovine homologue is expressed on bovine NK cells (Storset, A.K. et al.) and no expression of CD335 has been detected on B cells, T cells, monocytes or granulocytes.
Store at -20 °C only.
This product should be stored undiluted.
Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Purified IgG - liquid
Phosphate buffered saline
Quality Control (Contaminants):
Fusion protein consisting of the extracellular region of bovine CD335.
Spleen cells from immunised Balb/c mice were fused with cells of the NS-0 myeloma cell line.