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Mouse Anti-Bovine Osteocalcin

Mouse Anti-Bovine Osteocalcin

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DS-MB-02042
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Antigen Information

Protein Name & Synonyms:
Osteocalcin
Target Species:
  • Bovine (cow)

Antibody Specifications

Applications:
ELISA
Concentration:
IgG concentration 1.0 mg/ml
Species Reactivity:
Bovine, Human, Pig, Rabbit, Rat

Specificity

This product recognizes intact human and bovine osteocalcin in a "2 site" assay and reacts with osteocalcin fragments corresponding to amino acids 15-31 and 20-43 of the native molecule. It does not recognize fragments representing amino acids 1-19 or 7-19 or intact bovine osteocalcin.

Osteocalcin (Bone Gla Protein) is a 49 amino acid single chain vitamin K dependent protein (MW 5.8 kDa), made by osteoblasts that is a major component of the non-collagenous bone matrix. Serum osteocalcin is elevated in diseases characterized by increased bone turnover such as osteoporosis, hyperparathyroidism and Paget❏'s disease, and low in conditions associated with low bone turnover such as hypoparathyroidism and growth hormone deficiency.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified

Preparation

Immunogen:
Native bovine osteocalcin
Preservative:
0.09%Sodium Azide (NaN3)

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.