Protein Name & Synonyms:
Cholera Toxin alpha
Preparation:
Ig fraction prepared by ammonium sulfate precipitation
Species Reactivity:
Bacterial
This product is specific for the alpha subunit of Cholera toxin.The cholera holotoxin consists of a pentameric ring of Beta subunits whose central pore is occupied by the Alpha subunit. The Alpha subunit contains two chains, A1 and A2, linked by a disulfide bridge. The Alpha subunit (and Cholera toxin) activates the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP.
Store at +4 °C. DO NOT FREEZE.
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Supplied as:
Ig fraction - liquid
Formulation:
Phosphate buffered saline
Ig fraction prepared by ammonium sulfate precipitation
Immunogen:
Vibrio cholerae extract