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Antigen Information
Protein Name & Synonyms:
Diphtheria Toxin A
Target Species:
- Bacterial
Antibody Specifications
Applications:
ELISA
Concentration:
IgG concentration 0.1 mg/ml
Species Reactivity:
Bacterial
Specificity
This product recognizes diphtheria toxin (DT), secreted by certain strains of Corynebacterium diphtheriae. DT catalyzes the ADP-ribosylation of eukaryotic aminoacyl-transferase II (EF-2) using NAD as a substrate. This reaction forms the basis for its toxicity toward eukaryotic organisms. The toxin is secreted as a single polypeptide chain of about 63kDa, it is then processed to form A and B fragments both of which appear to be required for toxicity.
This product recognizes both the free and bound A subunit of diphtheria toxin.
This product recognizes both the free and bound A subunit of diphtheria toxin.
Storage/Stability
Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Format
Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified
Preparation
Immunogen:
Native
Preservative:
0.09% Sodium Azide (NaN3)
1% Bovine Serum Albumin
1% Bovine Serum Albumin
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Ceyhan M., Ozsurekci Y., Aydin M., et al. Determination of the Presence of Diphtheria Toxin in the Myocardial Tissue of Rabbits and a Female Subject by Using an Immunofluorescent Antibody Method. J Clin Med Res. 2015 Jun;7(6):472-8. doi: 10.14740/jocmr2142w.
Species: Other
Sample type: Tissue Lysate
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Usage
This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.
