Protein Name & Synonyms:
Diphtheria Toxin A
Concentration:
IgG concentration 0.1 mg/ml
Species Reactivity:
Bacterial
This product recognizes diphtheria toxin (DT), secreted by certain strains of Corynebacterium diphtheriae. DT catalyzes the ADP-ribosylation of eukaryotic aminoacyl-transferase II (EF-2) using NAD as a substrate. This reaction forms the basis for its toxicity toward eukaryotic organisms. The toxin is secreted as a single polypeptide chain of about 63kDa, it is then processed to form A and B fragments both of which appear to be required for toxicity.
This product recognizes both the free and bound A subunit of diphtheria toxin.
Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Preservative:
0.09% Sodium Azide (NaN3)
1% Bovine Serum Albumin