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Mouse Anti-Diphtheria Toxin

Mouse Anti-Diphtheria Toxin

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DS-MB-01174
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Antigen Information

Protein Name & Synonyms:
Diphtheria Toxin
Target Species:
  • Bacterial

Antibody Specifications

Applications:
ELISA
Concentration:
IgG concentration 0.1 mg/ml
Preparation:
Protein A chromatography
Species Reactivity:
Bacterial

Specificity

This product recognizes diphtheria toxin (DT), secreted by certain strains of Corynebacterium diphtheriae. DT catalyzes the ADP-ribosylation of eukaryotic aminoacyl-transferase II (EF-2) using NAD as a substrate. This reaction forms the basis for its toxicity toward eukaryotic organisms. The toxin is secreted as a single polypeptide chain of about 63kDa, it is then processed to form A and B fragments both of which appear to be required for toxicity.

This product is specific for the intact toxin/toxoid and does not react with free A or B subunits.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified

Preparation

Protein A chromatography

Immunogen:
Native
Preservative:
0.09%Sodium Azide (NaN3)

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.