Protein Name & Synonyms:
Immunohistology - Paraffin, Western Blotting
IgG concentration 1.0mg/ml
Synthetic Peptide, Chicken, Human, Mouse, Rabbit, Rat
This product detects a band of approximately 51kDa in Calu6 and HT29 cell lysates.
This product specifically recognizes hnRNP K (heterogeneous ribonucleotide protein K), a 464 amino acid acidic protein found in the nucleus, cytoplasm and mitochondria, shown to be involved in transcription, mRNA shuttling and the translation and editing of RNA.
Over-expression of hnRNP K has been demonstrated in cancerous tissue including that of the colon, breast, liver and lungs, and its involvement in cell migration has been implicated in tumour metastasis. Studies have also shown that hnRNP K increases the transcriptional activity of the c-myc and c-src oncogenes.
Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Purified IgG - liquid
Phosphate buffered saline
Ovalbumin-conjugated synthetic peptide SVKQYSGKFF