Mouse Anti-Human AFP

Mouse Anti-Human AFP

DS-MB-00070
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Antigen Information

Protein Name & Synonyms:
AFP
Target Species:
  • Human

Antibody Specifications

Applications:
ELISA
Concentration:
IgG concentration 1.0 mg/ml
Preparation:
Ig fraction prepared by chromatography
Species Reactivity:
Human

Specificity

This product recognizes alpha fetoprotein (AFP), a member of the albuminoid superfamily. It is a 68kD plasma protein found in fetuses over four weeks old, produced by the yolk sac and the fetal liver, with the highest concentration reached during the 12th to 16th week of gestation. It binds and transports various ligands such as bilirubin, fatty acids, steroids, heavy metals and various drugs. After birth, plasma levels drop to trace amounts in healthy adults.

Elevated AFP levels are indicative of certain cancers, particularly hepatocellular carcinoma, cancer of the testes or ovaries or a malignant teratoma. During pregnancy increased levels of AFP may indicate neural tube defects such as spina bifida, while decreased levels could indicate Down's syndrome.

This product does not cross-react with human albumin and other human serum proteins.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted.
Avoid repeated freezing and thawing as this may denature the antibody.
Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Ig fraction - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified

Preparation

Ig fraction prepared by chromatography

Immunogen:
Human fetal cord serum
Preservative:
0.09% Sodium Azide (NaN3)

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.