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Antigen Information

Protein Name & Synonyms:

Angiotensin I

Target Species:

Human

Antibody Specifications

Applications:

ELISA

Concentration:

IgG concentration 1.0 mg/ml

Immunogen Sequence:

P-F-H-L-V-I-H-N-E-S(-C)

Species Reactivity:

Human

Specificity

This product is specific for Angiotensin I and does not react with angiotensin II, III or angiotensinogen in ELISA.

Angiotensin I is important in the Renin-Angiotensin-Aldosterone System (RAAS). RAAS is responsible for the regulation of blood pressure and water retention in the body.

Angiotensin I is produced from a reaction between the renal enzyme Renin and angiotensinogen. It is converted by Angiotensin Converting Enzyme (ACE) into a vasoactive form called Angiotensin II which is responsible for increasing blood pressure.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:

Purified IgG - liquid

Formulation:

Phosphate buffered saline

Format Type:

Purified

Preparation

Immunogen:

Synthetic peptide corresponding to amino acids 40-49 of the angiotensinogen precursor (Swiss-Prot entry P01019) conjugated to HMW carrier protein.

Preservative:

0.09% Sodium Azide (NaN₃)

Amino Acid Sequence: