Mouse Anti-Human AURKA

Mouse Anti-Human AURKA

DS-MB-00101
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Antigen Information

Protein Name & Synonyms:
AURKA
Target Species:
  • Human

Antibody Specifications

Applications:
Immunofluorescence, Immunoprecipitation, Western Blotting
Concentration:
IgG concentration 1.0 mg/ml
Species Reactivity:
Human, Mouse

This product detects a band of approximately 46kDa in human HeLa and mouse M-ICc12 cell lysates.

Specificity

This product recognizes human Aurora-A kinase, a 46kDa serine/threonine kinase involved in mitotic spindle assembly.

Aurora-A is reported to be overexpressed in many epithelial cancers and is thought to play an important role in tumourigenesis.

This antibody recognizes an epitope within the non-catalytic N-terminal domain of Aurora-A. This product does not inhibit Aurora-A kinase activity.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.

This product should be stored undiluted.

Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified

Preparation

Immunogen:
Recombinant Aurora-A
Preservative:
0.09%Sodium Azide
This product
Spleen cells from immunised Balb/c were fused with cells of the SP2/0-Ag14 mouse myeloma cell line

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.