Mouse Anti-Human Bcl-10 [+RPE]

Mouse Anti-Human Bcl-10 [+RPE]

129-10050
+

Antigen Information

Protein Name & Synonyms:
Bcl-10
Target Species:
  • Human

Antibody Specifications

Applications:
Flow Cytometry
Host Species:
Mouse
Reconstitution:
Reconstitute with 1.0ml distilled water
Species Reactivity:
Human

Specificity

This product recognizes human B-cell lymphoma/leukaemia 10 (Bcl-10), a 31kD CARD (caspase recruitment domain) containing molecule that is involved in the regulation of apoptosis. Bcl-10 was originally identified through its direct involvement in t(1;14)(p22;q32) of mucosa-associated lymphoid tissue (MALT) lymphoma. The Bcl-10 molecule is predominantly located in the cytoplasm but expression has also been reported in the nucleus of some lymphomas.

Recent reports suggest that Bcl-10 is essential for nuclear factor (NF)-kappaB activation after lymphocyte receptor antigen stimulation and for the development of mature B-cells.

Storage/Stability

Store at +4 °C. DO NOT FREEZE.
This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 12 months after receipt.

Format

Supplied as:
Purified IgG conjugated to R. Phycoerythrin (RPE) - lyophilized
Formulation:
Phosphate buffered saline
Reconstitution:
Reconstitute with 1.0ml distilled water

Preparation

Immunogen:
Full length recombinant Bcl-10
Preservative:
0.09% Sodium Azide (NaN3)
1% Bovine Serum Albumin
5% Sucrose
This product
Spleen cells from immunised Balb/c mice were fused with cells of the NSO myeloma cell line.

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.