Mouse Anti-Human Bcl-10

Mouse Anti-Human Bcl-10

$347.00
129-10049
+

Antigen Information

Protein Name & Synonyms:
Bcl-10
Target Species:
  • Human

Antibody Specifications

Applications:
ELISA (dilution: 1/50, 1/800), Flow Cytometry, Immunoprecipitation, Immunohistology - Paraffin, Western Blotting
Concentration:
1.0 mg/ml
Host Species:
Mouse
Species Reactivity:
Human

This product detects bands of approximately 32kDa and 37kDa in cell lysates.

Specificity

This product recognizes human B-cell lymphoma/leukaemia 10 (Bcl-10), a 31kD CARD (caspase recruitment domain) containing molecule that is involved in the regulation of apoptosis. Bcl-10 was originally identified through its direct involvement in t(1;14)(p22;q32) of mucosa-associated lymphoid tissue (MALT) lymphoma. The Bcl-10 molecule is predominantly located in the cytoplasm but expression has also been reported in the nucleus of some lymphomas.

Recent reports suggest that Bcl-10 is essential for nuclear factor (NF)-kappaB activation after lymphocyte receptor antigen stimulation and for the development of mature B-cells.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified

Preparation

Immunogen:
Full length recombinant Bcl-10
Preservative:
0.09% Sodium Azide (NaN3)
This product
Spleen cells from immunised Balb/c mice were fused with cells of the NSO myeloma cell line.

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.