Mouse Anti-Human BNP / NPPB Pro (N-term)

Mouse Anti-Human BNP / NPPB Pro (N-term)

DS-MB-02777
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Antigen Information

Protein Name & Synonyms:
BNP / NPPB Pro
Target Species:
  • Human

Antibody Specifications

Applications:
ELISA, Immunoassay, Western Blotting
Concentration:
IgG concentration 1.0mg/ml
Species Reactivity:
Human

This product detects a band of approximately 9kDa when using recombinant NT-proBNP.

Specificity

This product detects the amino-terminal fragment of pro-brain natriuretic peptide (amino acids 13-20), also known as NT-proBNP, a cleavage product during the proteolytic activation of BNP. NT-proBNP is a secreted protein which is a member of the natriuretic peptide family, which is predominantly secreted from the cardiac ventricles in response to volume and pressure overload.

NT-proBNP is more stable than BNP in serum, and has become a useful biomarker of heart failure.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified

Preparation

Immunogen:
Amino acids 13-27 of NT-proBNP.
Preservative:
0.09%Sodium Azide (NaN3)
This product
Spleen cells from immunised Balb/c mice were fused with cells of the Sp2/0 myeloma cell line.

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.