Mouse Anti-Human C-Peptide

Mouse Anti-Human C-Peptide

$488.00
DS-MB-03275
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Antigen Information

Protein Name & Synonyms:
C-Peptide
Target Species:
  • Human

Antibody Specifications

Applications:
ELISA
Concentration:
IgG concentration 1.0mg/ml
Species Reactivity:
Human

Specificity

This product recognizes human C-peptide. C-peptide is a 31 amino acid peptide released when proinsulin is split into insulin and C-peptide. Proinsulin is split when it is released from the pancreas into the blood in response to a rise in serum glucose levels. C-peptide function is not fully understood, it binds to cell membranes which leads to increased intracellular Ca2+ concentration and subsequent stimulation of N+, K+-ATPase and endothelial nitric oxide synthase activities. C-peptide also functions in repair of the muscular layer of arteries. Levels of C-peptide can be used to distinguish between type 1 and type 2 diabetes. Patients with type 1 diabetes will usually have decreased levels of C-peptide, while patients with type 2 diabetes will have normal or higher than normal levels.

This product recognizes free C-peptide and proinsulin. It does not cross-react with human, bovine, porcine, mouse or rat insulin.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified

Preparation

Immunogen:
Recombinant C-peptide
Preservative:
0.09% Sodium Azide (NaN3)
Fusion Partners
Spleen cells from immunised Balb/c mice were fused with cells of the X63-Ag8-653 myeloma cell line.

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.