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Antigen Information
Protein Name & Synonyms:
C7
Target Species:
- Human
Antibody Specifications
Applications:
ELISA, Functional Assays, Western Blotting
Concentration:
IgG concentration 1.0 mg/ml
Species Reactivity:
Human
Specificity
This product recognizes complement component 7 (C7), a 110 kDa glycoprotein present in the blood serum. The factor I domain of C7 binds the C terminus of the C5 alpha-chain, acting as a membrane anchor. This enables the assembly of the complement membrane attack complex (MAC) and consequent complement lytic activity. C7 deficiency is associated with increased susceptibility to recurrent infections, in particular by Neisseria meningitides.
Note that This product does not recognize membrane bound complement membrane attack complex.
This product inhibits lysis of sensitised sheep erythrocytes.
Note that This product does not recognize membrane bound complement membrane attack complex.
This product inhibits lysis of sensitised sheep erythrocytes.
Storage/Stability
Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Format
Supplied as:
Purified IgG - liquid
Formulation:
Borate buffered saline
Format Type:
Purified
Preparation
Immunogen:
Purified human C7
Preservative:
0.1% Sodium Azide (NaN3)
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Usage
This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.
