Protein Name & Synonyms:
ELISA, Functional Assays, Western Blotting
Concentration (lot specific):
IgG concentration 1.0 mg/ml
This product recognizes complement component 7 (C7), a 110 kDa glycoprotein present in the blood serum. The factor I domain of C7 binds the C terminus of the C5 alpha-chain, acting as a membrane anchor. This enables the assembly of the complement membrane attack complex (MAC) and consequent complement lytic activity. C7 deficiency is associated with increased susceptibility to recurrent infections, in particular by Neisseria meningitides.
Note that This product does not recognize membrane bound complement membrane attack complex.
This product inhibits lysis of sensitised sheep erythrocytes.
Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Purified IgG - liquid
Borate buffered saline
Purified human C7
0.1% Sodium Azide (NaN3)
12 months from the date of shipment when stored properly.