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Antigen Information
Protein Name & Synonyms:
CBb (Neoantigen)
Target Species:
- Human
Antibody Specifications
Applications:
ELISA, Flow Cytometry, Western Blotting
Concentration:
IgG concentration 1.0 mg/ml
Species Reactivity:
Human
Specificity
This product recognizes a neoantigen of the Bb fragment of human complement factor B. Factor B is present in blood serum. C3b associates with complement factor B, inducing conformational change. This enables complement factor D to cleave the N-terminal of complement factor B (the Ba subunit) leaving the 63 kDa Bb subunit associated with C3b and forming C3 convertase. Subunit Bb is involved in the proliferation of preactivated B lymphocytes. Conversely, Ba inhibits lymphocyte proliferation.
Storage/Stability
Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Format
Supplied as:
Purified IgG - liquid
Formulation:
Borate buffered saline
Format Type:
Purified
Preparation
Immunogen:
Purified Human factor B
Preservative:
| 0.02% | Sodium Azide (NaN3) |
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Usage
This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.
