Protein Name & Synonyms:
Flow Cytometry, Immunohistology - Paraffin
IgG concentration 1.0 mg/ml
This product specifically recognizes human CD107a, otherwise known as LAMP-1 (lysosome-associated membrane protein-1), a 100-120kDa type I integral lysosomal membrane glycoprotein and member of the LAMP family, which transfers between lysosomes, phagosomes and the plasma membrane, and may play a role in lysosomal membrane protection and in lectin-mediated cell adhesion.
Studies have linked enhanced CD107a expression with the metastatic potential of some tumour cells, and with neurones and glial cells surrounding plaques in Alzheimer's patients. CD107a may also serve as a marker of mast cell activation.
Store at -20 °C only.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Purified IgG - liquid
Phosphate buffered saline
Human U937 caucasian hystiocytic lymphoma cell line.