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Antigen Information
Protein Name & Synonyms:
CD11b
Target Species:
- Human
Antibody Specifications
Applications:
Flow Cytometry
Concentration:
IgG concentration 0.1 mg/ml
Species Reactivity:
Human, Cynomolgus monkey, Rhesus monkey and Baboon tissues Does not cross react with feline tissues
Specificity
This product recognizes the human CD11b cell surface glycoprotein, a 165kD molecule also known as the alpha M integrin, MAC-1 and CR3. This molecule is expressed as a heterodimer in association with the beta 2 integrin, and is found upon monocytes, granulocytes, NK cells and some peripheral blood lymphocytes.
This antibody has been reported to have various functional effects on monocytes, blocking adhesion and stimulating cytokine and chemokine release.
This antibody has been reported to have various functional effects on monocytes, blocking adhesion and stimulating cytokine and chemokine release.
Storage/Stability
Store at +4 °C or at -20 °C if preferred.
This product should be stored undiluted.
Storage in frost-free freezers is not recommended. This product is photosensitive and should be protected from light.
Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Format
Supplied as:
Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid
Formulation:
Phosphate buffered saline
Preparation
Immunogen:
Rheumatoid synovial cells and human monocytes
Preservative:
| 0.09% | Sodium Azide |
| 1% | Bovine Serum Albumin |
This product
Spleen cells from immunised BALB/c mice were fused with cells of the mouse Sp2/0 myeloma cell line.
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Usage
This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.
