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Product Specifications

Size:

100 TESTS

Protein Information

Protein Name & Synonyms:

CD11b4

Target Species:

Human

Antibody Specifications

Applications:

Flow Cytometry

Reconstitution:

Reconstitute with 1 ml distilled water

Species Reactivity:

Human, Cynomolgus monkey, Rhesus monkey and Baboon tissues Does not cross react with feline tissues

Specificity

This product recognizes the human CD11b cell surface antigen, also known as the alphaM integrin. CD11b forms a heterodimer with CD18 and is expressed by circulating monocytes, granulocytes and also by dendritic reticulum cells in lymphoid tissue. Expression is increased on activated granulocytes.

The CD11b molecule is the receptor for C3bi, fibrinogen and clotting factor X.

This antibody has been reported to have various functional effects on monocytes, blocking adhesion and stimulating cytokine and chemokine release.

Storage/Stability

Prior to reconstitution store at +4 °C. Following reconstitution store at +4 °C.

DO NOT FREEZE.

This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 12 months after receipt.

Format

Supplied as:

Purified IgG conjugated to R. Phycoerythrin (RPE) - lyophilized

Formulation:

Phosphate buffered saline

Reconstitution:

Reconstitute with 1 ml distilled water

Preparation

Immunogen:

Rheumatoid Synovial cells and Human Monocytes

Preservative:

0.09%	Sodium Azide
1%	Bovine Serum Albumin
5%	Sucrose

This product

Spleen cells from immunised BALB/c mice were fused with cells of the SP2 mouse myeloma cell line.

Expiration:

12 months from the date of shipment when stored properly.