Protein Name & Synonyms:
Immunohistology - Frozen, ELISA (dilution: 1/50 , 1/100), Flow Cytometry
IgG concentration 1.0 mg/ml
This product recognizes the 118kD cell surface glycoprotein CD146, also known as MUC18, Mel-CAM and S-endo. CD146 is a member of the immunoglobulin superfamily, expressed by all endothelial cells and by melanoma cells.
CD146 appears to act as an adhesion molecule. Expression in melanoma may be linked to tumour progression.
Store at -20 °C only.
This product should be stored undiluted.
Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Purified IgG - liquid
Phosphate buffered saline
Recombinant human MUC18 (D1-D5) Fc protein.
Spleen cells from immunised mice were fused with cells of the mouse Sp2/0 Ag.14 myeloma cell line.