Mouse Anti-Human CD146, azide-free

Mouse Anti-Human CD146, azide-free (1 mg)
CODE:  DS-MB-00346

Antigen Information

Protein Name & Synonyms:
CD146
Target Species:
  • Human

Antibody Specifications

Applications:
Immunohistology - Frozen, ELISA (dilution: 1/50 , 1/100), Flow Cytometry
Concentration:
IgG concentration 1.0 mg/ml
Species Reactivity:
Human, Pig

Specificity

This product recognizes the 118kD cell surface glycoprotein CD146, also known as MUC18, Mel-CAM and S-endo. CD146 is a member of the immunoglobulin superfamily, expressed by all endothelial cells and by melanoma cells.

CD146 appears to act as an adhesion molecule. Expression in melanoma may be linked to tumour progression.

Storage/Stability

Store at -20 °C only.

This product should be stored undiluted.

Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Format Type:
Azide Free

Preparation

Immunogen:
Recombinant human MUC18 (D1-D5) Fc protein.
Preservative:
None present
This product
Spleen cells from immunised mice were fused with cells of the mouse Sp2/0 Ag.14 myeloma cell line.