Mouse Anti-Human CD16

Mouse Anti-Human CD16 (0.1 mg)

DS-MB-02836
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Antigen Information

Protein Name & Synonyms:
CD16
Target Species:
  • Human

Antibody Specifications

Applications:
Flow Cytometry, Immunoprecipitation
Concentration:
IgG concentration 1.0 mg/ml
Species Reactivity:
Human

Specificity

This product recognizes CD16, a 50-65kD cell surface molecule which exists in two forms - a transmembranous form expressed by NK cells and some T cells, and a phosphatidylinositol linked form expressed by granulocytes.

CD16 is a low affinity receptor for IgG (FcR III), and is an important receptor mediating ADCC by NK cells. This product has been reported to block the binding of IgG to the CD16 molecule, see Tamm, A. and Schmidt, R.E. for details.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.

This product should be stored undiluted.

Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified

Preparation

Immunogen:
Normal human peripheral blood granulocytes
Preservative:
0.09%Sodium Azide
This product
Spleen cells from immunised BALB/c mice were fused with cells of the mouse X63.653 myeloma cell line.

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.