Mouse Anti-Human CD172g [+FITC]

Mouse Anti-Human CD172g [+FITC] (0.1 mg)

$412.00
DS-MB-02855
+

Antigen Information

Protein Name & Synonyms:
CD172g
Target Species:
  • Human

Antibody Specifications

Applications:
Flow Cytometry
Concentration:
IgG concentration 0.1mg/ml
Species Reactivity:
Human

Specificity

This product recognizes human SIRP gamma, a 55kD signal regulatory protein which is a member of the immunoglobulin gene superfamily. SIRP gamma, also known as CD172g, is expressed on most T lymphocytes and a subset of B-cells but is absent on myeloid cells. CD172g has a truncated cytoplasmic tail, which is similar to SIRP beta, but unlike SIRP beta CD172g does not require DAP12 for expression at the cell surface. CD172g, like SIRP alpha, binds to CD47 inducing apoptosis. It is also involved in the negative regulation of receptor tyrosine kinase-coupled signalling.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid
Formulation:
Phosphate buffered saline

Preparation

Immunogen:
Purified recombinant SIRPgamma.CD4.
Preservative:
0.09%Sodium Azide (NaN3)
1%Bovine Serum Albumin
This product
Spleen cells from immunised BALB/c mice were fused with cells of the NS-1 myeloma cell line.

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.